Identification of undiagnosed dementia cases using a web-based pre-screening tool: The MOPEAD project.
Alzheimer's disease
diagnostic gap
early diagnosis
patient engagement
population-based screening
Journal
Alzheimer's & dementia : the journal of the Alzheimer's Association
ISSN: 1552-5279
Titre abrégé: Alzheimers Dement
Pays: United States
ID NLM: 101231978
Informations de publication
Date de publication:
08 2021
08 2021
Historique:
revised:
29
12
2020
received:
19
02
2020
accepted:
01
01
2021
pubmed:
17
4
2021
medline:
20
11
2021
entrez:
16
4
2021
Statut:
ppublish
Résumé
Innovative patient engagement models are required to identify people with prodromal and mild Alzheimer's disease who are "hidden" in their communities and not normally found in a memory clinic setting. A marketing campaign and a web-based pre-screening tool were used to identify individuals at risk of dementia in five European countries. Harmonized clinical evaluation of these patients was performed in participating memory clinics within the MOPEAD project. A total of 1487 individuals completed the pre-screening, with 547 of them found to be at risk of dementia (36.8%). Among the subset of 91 patients with a positive pre-screening result that underwent full clinical evaluation, 49 (53.8%) were diagnosed with either mild cognitive impairment or Alzheimer's disease. This novel web-based pre-screening tool showed to be a valid strategy to identify undiagnosed people with cognitive impairment.
Identifiants
pubmed: 33860599
doi: 10.1002/alz.12297
pmc: PMC8453736
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1307-1316Informations de copyright
© 2021 The Authors. Alzheimer's & Dementia published by Wiley Periodicals LLC on behalf of Alzheimer's Association.
Références
Dement Geriatr Cogn Disord. 2001 Jul-Aug;12(4):265-80
pubmed: 11351138
J Med Internet Res. 2014 Oct 07;16(10):e224
pubmed: 25348028
Nicotine Tob Res. 2014 Feb;16(2):247-51
pubmed: 24127266
Front Behav Neurosci. 2013 Jul 23;7:89
pubmed: 23888131
Neuropsychologia. 2011 Jun;49(7):2060-70
pubmed: 21477602
Alzheimers Dement (Amst). 2018 Nov 12;11:36-44
pubmed: 30623017
Internet Interv. 2016 Apr 27;4:72-81
pubmed: 30135792
J Alzheimers Dis. 2015;49(3):617-31
pubmed: 26484931
Neurobiol Aging. 2017 May;53:1-10
pubmed: 28189924
Sci Transl Med. 2011 Nov 30;3(111):111cm33
pubmed: 22133718
Aging Ment Health. 2013;17(1):77-84
pubmed: 22690732
Int J Geriatr Psychiatry. 2005 Apr;20(4):377-86
pubmed: 15799080
J Alzheimers Dis. 2018;62(3):1079-1090
pubmed: 29562541
J Alzheimers Dis. 2015 Sep 24;48 Suppl 1:S99-S107
pubmed: 26402087
Alzheimers Res Ther. 2012 Sep 21;4(5):40
pubmed: 22995353
Neurology. 1993 Nov;43(11):2412-4
pubmed: 8232972
Alzheimers Dement. 2019 Jun;15(6):828-839
pubmed: 31076376
Brain. 1988 Jun;111 ( Pt 3):695-718
pubmed: 3382917
Alzheimers Dement. 2021 Aug;17(8):1307-1316
pubmed: 33860599