Development of an enzyme-linked immunosorbent assay for the detection of mebendazole in chicken and mutton.
Journal
Analytical methods : advancing methods and applications
ISSN: 1759-9679
Titre abrégé: Anal Methods
Pays: England
ID NLM: 101519733
Informations de publication
Date de publication:
14 04 2021
14 04 2021
Historique:
entrez:
16
4
2021
pubmed:
17
4
2021
medline:
15
5
2021
Statut:
ppublish
Résumé
Mebendazole (MBZ), a synthetic benzimidazole, is most widely used for the treatment of intestinal helminthiasis. In the present study, a hapten mimicking the MBZ structure was designed by introducing propanoic acid and coupling to carrier proteins by the active ester method to immunize New Zealand rabbits. A sensitive enzyme-linked immunosorbent assay (ELISA) was developed for the analysis of MBZ in food samples. The rabbit IgG based ELISA had a half-maximum inhibition concentration (IC
Substances chimiques
Fenbendazole
621BVT9M36
Mebendazole
81G6I5V05I
Albendazole
F4216019LN
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM