Fertility preservation in women with peritoneal surface malignancies: A case series.
Cytoreductive surgery
Fertility preservation
Hyperthermic intraperitoneal chemotherapy
Infertility
Oocyte
Primary peritoneal disease
Journal
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
ISSN: 1532-2157
Titre abrégé: Eur J Surg Oncol
Pays: England
ID NLM: 8504356
Informations de publication
Date de publication:
11 2021
11 2021
Historique:
received:
12
01
2021
revised:
23
03
2021
accepted:
28
03
2021
pubmed:
18
4
2021
medline:
6
1
2022
entrez:
17
4
2021
Statut:
ppublish
Résumé
The advent of cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) has improved survival in patients with peritoneal surface malignancies. Not surprisingly, there is now a growing interest on the possible means to preserve fertility to ensure future childbearing. In this study, we report on five women with peritoneal surface malignancies who performed ovarian hyper-stimulation and oocytes cryostorage prior to undergo CRS and HIPEC. The presence of the disease complicated follicular growth monitoring but the oocytes retrievals could be always performed and were uneventful. At last follow-up, all women were alive and disease-free. None has yet returned to thaw her oocytes. Overall, these cases suggest that oocytes cryopreservation before CRS and HIPEC should be considered.
Identifiants
pubmed: 33863607
pii: S0748-7983(21)00404-2
doi: 10.1016/j.ejso.2021.03.259
pii:
doi:
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2948-2951Informations de copyright
Copyright © 2021 Elsevier Ltd, BASO ~ The Association for Cancer Surgery, and the European Society of Surgical Oncology. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest Edgardo Somigliana reports grants from Ferring, grants and personal fees from Merck, grants and personal fees from Theramex, outside the submitted work. All the other authors do not have any conflict of interest to declare.