SARS-CoV-2 seroprevalence in healthcare workers at a frontline hospital in Tokyo.

Adult Aged Antibodies, Viral / blood COVID-19 / diagnosis Cross-Sectional Studies Female Health Personnel Hospitals Humans Male Middle Aged SARS-CoV-2 / isolation & purification Tokyo / epidemiology Young Adult

Journal

Scientific reports

ISSN: 2045-2322

Titre abrégé: Sci Rep

Pays: England

ID NLM: 101563288

Informations de publication

Date de publication:
16 04 2021

Historique:

received: 01 03 2021

accepted: 25 03 2021

entrez: 17 4 2021

pubmed: 18 4 2021

medline: 4 5 2021

Statut: epublish

Résumé

Healthcare workers (HCWs) are highly exposed to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The actual coronavirus disease (COVID-19) situation, especially in regions that are less affected, has not yet been determined. This study aimed to assess the seroprevalence of SARS-CoV-2 in HCWs working in a frontline hospital in Tokyo, Japan. In this cross-sectional observational study, screening was performed on consented HCWs, including medical, nursing, and other workers, as part of a mandatory health checkup. The screening test results and clinical characteristics of the participants were recorded. The antibody seroprevalence rate among the 4147 participants screened between July 6 and August 21, 2020, was 0.34% (14/4147). There was no significant difference in the seroprevalence rate between frontline HCWs with a high exposure risk and HCWs working in other settings with a low exposure risk. Of those seropositive for SARS-CoV-2, 64% (9/14) were not aware of any symptoms and had not previously been diagnosed with COVID-19. In conclusion, this study provides insights into the extent of infection and immune status in HCWs in Japan, which has a relatively low prevalence of COVID-19. Our findings aid in formulating public health policies to control virus spread in regions with low-intensity COVID-19.

Identifiants

DOI: 10.1038/s41598-021-87688-9 PMID: 33863960 PMC: PMC8052331

pubmed: 33863960

doi: 10.1038/s41598-021-87688-9

pii: 10.1038/s41598-021-87688-9

pmc: PMC8052331

doi:

Substances chimiques

Antibodies, Viral 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

Pagination

8380

Commentaires et corrections

Type : ErratumIn

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