Interscan measurement error of knee cartilage thickness and projected cartilage area ratio at 9 regions and 45 subregions by fully automatic three-dimensional MRI analysis.


Journal

European journal of radiology
ISSN: 1872-7727
Titre abrégé: Eur J Radiol
Pays: Ireland
ID NLM: 8106411

Informations de publication

Date de publication:
Jun 2021
Historique:
received: 01 11 2020
revised: 17 02 2021
accepted: 04 04 2021
pubmed: 18 4 2021
medline: 19 5 2021
entrez: 17 4 2021
Statut: ppublish

Résumé

We have developed a fully automatic three-dimensional MRI analysis software program for automatic segmentation of knee cartilage using a deep neural network. The purpose of this study was to use this software to clarify the interscan measurement error of the knee cartilage thickness and projected cartilage area ratio at 9 regions and 45 subregions in the knee. Ten healthy volunteers underwent MRI twice in the same day. The software provided cartilage thickness and projected cartilage area ratio (thickness ≥ 1.5 mm) at 9 regions and 45 subregions of the knee without any manual correction. The interscan measurement error was calculated at each region and subregion from the data of nine donors, except for one donor who had body motion during the MRI examination. The interscan measurement error of cartilage thickness was less than 0.10 mm at all 9 regions and at 39 subregions among 45 subregions. The measurement errors ranged from 0.03 to 0.21 mm. The intraclass correlation coefficients (ICC) of cartilage thickness were higher than 0.75 at all 9 regions and 41 subregions. The interscan measurement error of the projected cartilage area ratio ranged from 0.01 to 0.03 for all 9 regions. This study clarified the interscan measurement error of the knee cartilage thickness and projected cartilage area ratio.

Sections du résumé

BACKGROUND BACKGROUND
We have developed a fully automatic three-dimensional MRI analysis software program for automatic segmentation of knee cartilage using a deep neural network. The purpose of this study was to use this software to clarify the interscan measurement error of the knee cartilage thickness and projected cartilage area ratio at 9 regions and 45 subregions in the knee.
METHODS METHODS
Ten healthy volunteers underwent MRI twice in the same day. The software provided cartilage thickness and projected cartilage area ratio (thickness ≥ 1.5 mm) at 9 regions and 45 subregions of the knee without any manual correction. The interscan measurement error was calculated at each region and subregion from the data of nine donors, except for one donor who had body motion during the MRI examination.
RESULTS RESULTS
The interscan measurement error of cartilage thickness was less than 0.10 mm at all 9 regions and at 39 subregions among 45 subregions. The measurement errors ranged from 0.03 to 0.21 mm. The intraclass correlation coefficients (ICC) of cartilage thickness were higher than 0.75 at all 9 regions and 41 subregions. The interscan measurement error of the projected cartilage area ratio ranged from 0.01 to 0.03 for all 9 regions.
CONCLUSIONS CONCLUSIONS
This study clarified the interscan measurement error of the knee cartilage thickness and projected cartilage area ratio.

Identifiants

pubmed: 33865065
pii: S0720-048X(21)00180-7
doi: 10.1016/j.ejrad.2021.109700
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

109700

Informations de copyright

Copyright © 2021 The Authors. Published by Elsevier B.V. All rights reserved.

Auteurs

Ichiro Sekiya (I)

Center for Stem Cell and Regenerative Medicine, Tokyo Medical and Dental University, Japan. Electronic address: sekiya.arm@tmd.ac.jp.

Yuji Kohno (Y)

Center for Stem Cell and Regenerative Medicine, Tokyo Medical and Dental University, Japan. Electronic address: kohno.arm@tmd.ac.jp.

Akinobu Hyodo (A)

Center for Stem Cell and Regenerative Medicine, Tokyo Medical and Dental University, Japan. Electronic address: hyodo.arm@tmd.ac.jp.

Hisako Katano (H)

Center for Stem Cell and Regenerative Medicine, Tokyo Medical and Dental University, Japan. Electronic address: katano.arm@tmd.ac.jp.

Keiichiro Komori (K)

Center for Stem Cell and Regenerative Medicine, Tokyo Medical and Dental University, Japan. Electronic address: komori.arm@tmd.ac.jp.

Hideyuki Koga (H)

Department of Joint Surgery and Sports Medicine, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Japan. Electronic address: koga.orj@tmd.ac.jp.

Makoto Tomita (M)

School of Data Science, Graduate School of Data Science, Yokohama City University, Japan. Electronic address: mtomita@ism.ac.jp.

Kenji Suzuki (K)

Fujifilm Corporation, Tokyo, Japan. Electronic address: kenji.suzuki@fujifilm.com.

Jun Masumoto (J)

Fujifilm Corporation, Tokyo, Japan. Electronic address: jun.masumoto@fujifilm.com.

Nobutake Ozeki (N)

Center for Stem Cell and Regenerative Medicine, Tokyo Medical and Dental University, Japan. Electronic address: ozeki.arm@tmd.ac.jp.

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