Outcomes and Risk Factors for Cardiovascular Events in Hospitalized COVID-19 Patients.


Journal

Journal of cardiothoracic and vascular anesthesia
ISSN: 1532-8422
Titre abrégé: J Cardiothorac Vasc Anesth
Pays: United States
ID NLM: 9110208

Informations de publication

Date de publication:
12 2021
Historique:
received: 01 01 2021
revised: 18 03 2021
accepted: 21 03 2021
pubmed: 20 4 2021
medline: 19 11 2021
entrez: 19 4 2021
Statut: ppublish

Résumé

To analyze outcomes and risk factors of cardiovascular events in a metropolitan coronavirus disease 2019 (COVID-19) database, and to perform a subgroup analysis in African American populations to determine whether outcomes and risk factors are influenced by race. Retrospective cohort analysis from March 9, 2020 to June 20, 2020. Population-based study in Louisville, KY, USA. Seven hundred adult inpatients hospitalized with COVID-19. N/A. This cohort consisted of 126 patients (18%) with cardiovascular events and 574 patients without cardiovascular events. Patients with cardiovascular events had a much higher mortality rate than those without cardiovascular events (45.2% v 8.7%, p < 0.001). There was no difference between African American and white patients regarding mortality (43.9% v 46.3%, p = 1) and length of stay for survivors (11 days v 9.5 days, p = 0.301). Multiple logistics regression analysis suggested that male, race, lower SaO2/F Cardiovascular events were prevalent and associated with worse outcomes in hospitalized patients with COVID-19. Outcomes of cardiovascular events in African American and white COVID-19 patients were similar after propensity score matching analysis. There were common and unique risk factors for cardiovascular events in African American COVID-19 patients when compared with white patients.

Identifiants

pubmed: 33867235
pii: S1053-0770(21)00277-9
doi: 10.1053/j.jvca.2021.03.035
pmc: PMC7997853
pii:
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

3581-3593

Subventions

Organisme : NIEHS NIH HHS
ID : P30 ES030283
Pays : United States
Organisme : NCATS NIH HHS
ID : U18 TR003787
Pays : United States

Informations de copyright

Copyright © 2021 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Conflict of Interest None.

Références

Eur Heart J. 2020 Jun 7;41(22):2070-2079
pubmed: 32391877
Nutr Metab Cardiovasc Dis. 2021 Jan 4;31(1):2-13
pubmed: 33229199
JAMA Cardiol. 2020 Nov 01;5(11):1265-1273
pubmed: 32730619
Lancet. 2020 May 2;395(10234):1417-1418
pubmed: 32325026
Hellenic J Cardiol. 2020 Nov-Dec;61(6):381-395
pubmed: 32534109
JAMA Cardiol. 2020 Jul 1;5(7):802-810
pubmed: 32211816
Lancet. 2020 Feb 15;395(10223):497-506
pubmed: 31986264
JACC Cardiovasc Imaging. 2020 Nov;13(11):2330-2339
pubmed: 32763118
Trends Endocrinol Metab. 2020 Dec;31(12):893-904
pubmed: 33172748
JAMA Cardiol. 2020 Jul 1;5(7):831-840
pubmed: 32219363
Nat Rev Immunol. 2020 Jun;20(6):363-374
pubmed: 32346093
Cardiovasc Res. 2020 May 1;116(6):1097-1100
pubmed: 32227090
EClinicalMedicine. 2020 Nov;28:100574
pubmed: 33052324
Prog Cardiovasc Dis. 2020 May - Jun;63(3):390-391
pubmed: 32169400
J Am Coll Cardiol. 2020 Jul 7;76(1):124-125
pubmed: 32407771
JAMA. 2020 Mar 17;323(11):1061-1069
pubmed: 32031570
JAMA Cardiol. 2020 Jul 1;5(7):811-818
pubmed: 32219356
SN Compr Clin Med. 2020;2(12):2514-2520
pubmed: 33052322
Chest. 2021 May;159(5):1974-1985
pubmed: 33129792
Lancet. 2020 Mar 28;395(10229):1054-1062
pubmed: 32171076
Biomarkers. 2020 Dec;25(8):634-640
pubmed: 33003961
Life Sci. 2020 Nov 1;260:118482
pubmed: 32971105
JAMA. 2020 Jul 28;324(4):390-392
pubmed: 32556085
JAMA Cardiol. 2020 Oct 1;5(10):1198
pubmed: 32639510
JAMA. 2020 May 19;323(19):1891-1892
pubmed: 32293639
Eur Heart J Acute Cardiovasc Care. 2020 Dec;9(8):817-823
pubmed: 33222494
Aging (Albany NY). 2020 Nov 23;12(23):23464-23477
pubmed: 33226958
Cell Res. 2020 May;30(5):367-369
pubmed: 32346073
Crit Care. 2020 Nov 16;24(1):647
pubmed: 33198786
Acta Biomed. 2020 Mar 19;91(1):157-160
pubmed: 32191675
Ann Epidemiol. 2021 Apr;56:47-54.e5
pubmed: 33181262
J Am Coll Cardiol. 2020 Nov 3;76(18):2043-2055
pubmed: 33121710
Nat Rev Cardiol. 2020 Sep;17(9):543-558
pubmed: 32690910
Mayo Clin Proc. 2020 Jun;95(6):1138-1147
pubmed: 32376101
JAMA Cardiol. 2020 Oct 1;5(10):1199-1200
pubmed: 32639516

Auteurs

Qian Xu (Q)

Department of Bioinformatics and Biostatistics, School of Public Health and Information Sciences, University of Louisville, Louisville, KY.

Harideep Samanapally (H)

Division of Infectious Diseases, Center of Excellence for Research in Infectious Diseases (CERID), University of Louisville, Louisville, KY.

Pavani Nathala (P)

Division of Infectious Diseases, Center of Excellence for Research in Infectious Diseases (CERID), University of Louisville, Louisville, KY.

Vidyulata Salunkhe (V)

Division of Infectious Diseases, Center of Excellence for Research in Infectious Diseases (CERID), University of Louisville, Louisville, KY.

Stephen Furmanek (S)

Division of Infectious Diseases, Center of Excellence for Research in Infectious Diseases (CERID), University of Louisville, Louisville, KY.

Meredith N Cahill (MN)

Division of Infectious Diseases, Center of Excellence for Research in Infectious Diseases (CERID), University of Louisville, Louisville, KY; School of Medicine, University of Louisville, Louisville, KY.

Trevor McGuffin (T)

School of Nursing, University of Louisville, Louisville, KY.

Tahboub Mohammad (T)

Division of Infectious Diseases, Center of Excellence for Research in Infectious Diseases (CERID), University of Louisville, Louisville, KY.

Bradford Marsili (B)

Department of Anesthesiology & Perioperative Medicine, University of Louisville, Louisville, KY.

Jessica Petrey (J)

Kornhauser Health Sciences Library, University of Louisville, Louisville, KY.

Ruth Carrico (R)

Division of Infectious Diseases, Center of Excellence for Research in Infectious Diseases (CERID), University of Louisville, Louisville, KY.

Julio Ramirez (J)

Division of Infectious Diseases, Center of Excellence for Research in Infectious Diseases (CERID), University of Louisville, Louisville, KY.

Ozan Akca (O)

Department of Anesthesiology & Perioperative Medicine, University of Louisville, Louisville, KY.

Sean P Clifford (SP)

Department of Anesthesiology & Perioperative Medicine, University of Louisville, Louisville, KY.

Siddharth Pahwa (S)

Department of Cardiovascular & Thoracic Surgery, University of Louisville, Louisville, KY.

Lynn Roser (L)

School of Nursing, University of Louisville, Louisville, KY.

Maiying Kong (M)

Department of Bioinformatics and Biostatistics, School of Public Health and Information Sciences, University of Louisville, Louisville, KY.

Jiapeng Huang (J)

Division of Infectious Diseases, Center of Excellence for Research in Infectious Diseases (CERID), University of Louisville, Louisville, KY; Department of Anesthesiology & Perioperative Medicine, University of Louisville, Louisville, KY; Department of Cardiovascular & Thoracic Surgery, University of Louisville, Louisville, KY; Center for Integrative Environmental Health Sciences, University of Louisville, Louisville, KY. Electronic address: jiapeng.huang@louisville.edu.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH