A Non-canonical Wnt Signature Correlates With Lower Survival in Gastric Cancer.
EMT
Frizzled-2
Frizzled-7
Ror2
Wnt
Wnt5a
gastric cancer
Journal
Frontiers in cell and developmental biology
ISSN: 2296-634X
Titre abrégé: Front Cell Dev Biol
Pays: Switzerland
ID NLM: 101630250
Informations de publication
Date de publication:
2021
2021
Historique:
received:
26
11
2020
accepted:
24
02
2021
entrez:
19
4
2021
pubmed:
20
4
2021
medline:
20
4
2021
Statut:
epublish
Résumé
Genetic evidence suggests a role for the Wnt/β-catenin pathway in gastric cancer. However, Wnt5a, regarded as a prototypical non-canonical Wnt ligand, has also been extensively associated with this disease. Therefore, the roles of the Wnt signaling pathway in gastric cancer initiation and progression, and particularly the precise mechanisms by which the non-canonical Wnt pathway might promote the development and progression of gastric cancer, are not entirely well understood. This article analyzes publicly available gene and protein expression data and reveals the existence of a
Identifiants
pubmed: 33869179
doi: 10.3389/fcell.2021.633675
pmc: PMC8047116
doi:
Types de publication
Journal Article
Langues
eng
Pagination
633675Informations de copyright
Copyright © 2021 Astudillo.
Déclaration de conflit d'intérêts
The author declares that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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