Animals Antimalarials / chemistry Aspartic Acid Endopeptidases Aspartic Acid Proteases / pharmacology Folic Acid Antagonists / pharmacology Malaria Molecular Docking Simulation Molecular Dynamics Simulation Piperazines Plasmodium falciparum Protease Inhibitors / chemistry Saquinavir / pharmacology
In silico antimalarial drug design plasmepsin

Journal

Journal of biomolecular structure & dynamics
ISSN: 1538-0254
Titre abrégé: J Biomol Struct Dyn
Pays: England
ID NLM: 8404176

Informations de publication

Date de publication:
11 2022
Historique:
pubmed: 20 4 2021
medline: 19 10 2022
entrez: 19 4 2021
Statut: ppublish

Résumé

Plasmepsin V (Plm V) is an essential aspartic protease required for survival of the malaria parasite,

Identifiants

DOI: 10.1080/07391102.2021.1911855 PMID: 33870856
pubmed: 33870856
doi: 10.1080/07391102.2021.1911855
doi:

Substances chimiques

Antimalarials 0
Folic Acid Antagonists 0
Piperazines 0
Protease Inhibitors 0
Aspartic Acid Proteases EC 3.4.-
Aspartic Acid Endopeptidases EC 3.4.23.-
plasmepsin EC 3.4.23.38
Saquinavir L3JE09KZ2F

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

8352-8364

Auteurs

Prem Prakash Sharma (PP)

Department of Biomedical Engineering, Deenbandhu Chhotu Ram, University of Science & Technology, Murthal, Sonepat, Haryana, India.
Laboratory for Translational Chemistry and Drug Discovery, Department of Chemistry, Hansraj College, University of Delhi, Delhi, India.

Sumit Kumar (S)

Department of Chemistry, Miranda House, University of Delhi, Delhi, India.

Kumar Kaushik (K)

Centre for Fire, Explosives & Environment Safety, Fire Chemistry Group, Delhi, India.

Archana Singh (A)

Department of Botany, Hansraj College, University of Delhi, Delhi, India.

Indrakant K Singh (IK)

Molecular Biology Research Lab., Department of Zoology, Deshbandhu College, University of Delhi, Delhi, India.

Maria Grishina (M)

Laboratory of Computational Modelling of Drugs, South Ural State University, Russia.
ORCID: 0000-0002-2573-4831

Kailash C Pandey (KC)

Host-Parasite Interaction Biology Group, National Institute of Malaria Research, New Delhi, India.

Pushpendra Singh (P)

Helix BioGenesis, Sector-2, Noida, Uttar Pradesh, India.

Vladimir Potemkin (V)

Laboratory of Computational Modelling of Drugs, South Ural State University, Russia.
ORCID: 0000-0002-5244-8718
Department of Chemistry, Miranda House, University of Delhi, Delhi, India.

Geeta Singh (G)

Department of Biomedical Engineering, Deenbandhu Chhotu Ram, University of Science & Technology, Murthal, Sonepat, Haryana, India.

Brijesh Rathi (B)

Laboratory for Translational Chemistry and Drug Discovery, Department of Chemistry, Hansraj College, University of Delhi, Delhi, India.
Laboratory of Computational Modelling of Drugs, South Ural State University, Russia.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux ›
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antiparasitaires › Antiprotozoaires › Antipaludiques ›
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Hydrolases › Peptide hydrolases › Endopeptidases › Aspartic acid endopeptidases ›
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Hydrolases › Peptide hydrolases › Aspartic acid proteases ›
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Mécanismes moléculaires de l'action pharmacologique › Antienzymes › Antifoliques ›
questionsmedicales.fr › Infection › Maladies vectorielles › Paludisme ›
questionsmedicales.fr › Sciences de l'information › Méthodologies informatiques › Simulation numérique › Simulation de docking moléculaire ›
questionsmedicales.fr › Sciences de l'information › Méthodologies informatiques › Simulation numérique › Simulation de dynamique moléculaire ›
questionsmedicales.fr › Composés hétérocycliques › Composés hétéromonocycliques › Pipérazines ›
questionsmedicales.fr › Eucaryotes › Alveolata › Apicomplexa › Haemosporida › Plasmodium › Plasmodium falciparum ›
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Mécanismes moléculaires de l'action pharmacologique › Antienzymes › Inhibiteurs de protéases ›
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Quinoléines › Saquinavir ›