A semiautomated method to quantitatively assess osteolytic lesion volume and bone mineral density within acetabular regions of interest from CT.


Journal

Journal of orthopaedic research : official publication of the Orthopaedic Research Society
ISSN: 1554-527X
Titre abrégé: J Orthop Res
Pays: United States
ID NLM: 8404726

Informations de publication

Date de publication:
02 2022
Historique:
revised: 25 03 2021
received: 19 11 2020
accepted: 12 04 2021
pubmed: 20 4 2021
medline: 19 4 2022
entrez: 19 4 2021
Statut: ppublish

Résumé

The objectives of this study were to (1) develop a semiautomated method to obtain lesion volume and bone mineral density (BMD) in terms of Hounsfield units from pelvic computed tomography (CT) scans in three regions of interest, and (2) assess accuracy and reliability of the method based on cadaveric CT scans. Image artefacts due to metal implants reduce CT clarity and are more severe with more than one implant in situ. Therefore, accuracy and reliability tests were performed with varying numbers of total hip arthroplasties implanted. To test the accuracy of lesion size measurements, microcomputed tomography was used as a reference. Mean absolute error ranged from 36 to 284 mm

Identifiants

pubmed: 33871103
doi: 10.1002/jor.25051
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

396-408

Informations de copyright

© 2021 Orthopaedic Research Society. Published by Wiley Periodicals LLC.

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Auteurs

Thomas M Grace (TM)

Centre of Orthopaedic & Trauma Research, University of Adelaide, Adelaide, South Australia, Australia.

Dermot O'Rourke (D)

Medical Device Research Institute, College of Science and Engineering, Flinders University, Adelaide, South Australia, Australia.

Thomas Robertson (T)

Centre of Orthopaedic & Trauma Research, University of Adelaide, Adelaide, South Australia, Australia.
Royal Adelaide Hospital, Adelaide, South Australia, Australia.

Egon Perilli (E)

Medical Device Research Institute, College of Science and Engineering, Flinders University, Adelaide, South Australia, Australia.

Stuart Callary (S)

Centre of Orthopaedic & Trauma Research, University of Adelaide, Adelaide, South Australia, Australia.
Royal Adelaide Hospital, Adelaide, South Australia, Australia.

Mark Taylor (M)

Medical Device Research Institute, College of Science and Engineering, Flinders University, Adelaide, South Australia, Australia.

Gerald J Atkins (GJ)

Centre of Orthopaedic & Trauma Research, University of Adelaide, Adelaide, South Australia, Australia.

Lucian B Solomon (LB)

Centre of Orthopaedic & Trauma Research, University of Adelaide, Adelaide, South Australia, Australia.
Royal Adelaide Hospital, Adelaide, South Australia, Australia.

Dominic Thewlis (D)

Centre of Orthopaedic & Trauma Research, University of Adelaide, Adelaide, South Australia, Australia.

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