Patent foramen ovale revealed by COVID-19 pneumonia.
COVID-19
/ diagnosis
Dyspnea
/ diagnosis
Echocardiography
/ methods
Foramen Ovale, Patent
/ complications
Hemodynamics
Humans
Hypoxia
/ diagnosis
Lung
/ diagnostic imaging
Lung Diseases, Interstitial
/ complications
Male
Middle Aged
Oxygen
/ analysis
Pneumonia, Viral
/ complications
Posture
/ physiology
SARS-CoV-2
/ isolation & purification
Syndrome
Treatment Outcome
Hypoxemia
Patent foramen ovale
Pulmonary vasoconstriction
SARS-CoV-2
Ventilation inhomogeneity
Journal
BMC pulmonary medicine
ISSN: 1471-2466
Titre abrégé: BMC Pulm Med
Pays: England
ID NLM: 100968563
Informations de publication
Date de publication:
19 Apr 2021
19 Apr 2021
Historique:
received:
14
01
2021
accepted:
12
04
2021
entrez:
20
4
2021
pubmed:
21
4
2021
medline:
27
4
2021
Statut:
epublish
Résumé
Platypnea-orthodeoxia syndrome (POS) is a rare condition characterized by dyspnoea (platypnea) and arterial desaturation in the upright position resolved in the supine position (orthodeoxia). Intracardiac shunt, pulmonary ventilation-perfusion mismatch and others intrapulmonary abnormalities are involved. We report a case of POS associated with two pathophysiological issues: one, cardiac POS caused by a patent foramen ovale (PFO) and second, pulmonary POS due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) interstitial pneumonia. POS has resolved after recovery of coronavirus disease 2019 (COVID-19) pneumonia. Right-to-left interatrial shunt and intrapulmonary shunt caused by SARS-CoV-2 pneumonia contributed to refractory hypoxemia and POS. Therefore, in case of COVID-19 patient with unexplained POS, the existence of PFO must be investigated.
Sections du résumé
BACKGROUND
BACKGROUND
Platypnea-orthodeoxia syndrome (POS) is a rare condition characterized by dyspnoea (platypnea) and arterial desaturation in the upright position resolved in the supine position (orthodeoxia). Intracardiac shunt, pulmonary ventilation-perfusion mismatch and others intrapulmonary abnormalities are involved.
CASE PRESENTATION
METHODS
We report a case of POS associated with two pathophysiological issues: one, cardiac POS caused by a patent foramen ovale (PFO) and second, pulmonary POS due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) interstitial pneumonia. POS has resolved after recovery of coronavirus disease 2019 (COVID-19) pneumonia.
CONCLUSIONS
CONCLUSIONS
Right-to-left interatrial shunt and intrapulmonary shunt caused by SARS-CoV-2 pneumonia contributed to refractory hypoxemia and POS. Therefore, in case of COVID-19 patient with unexplained POS, the existence of PFO must be investigated.
Identifiants
pubmed: 33874930
doi: 10.1186/s12890-021-01494-7
pii: 10.1186/s12890-021-01494-7
pmc: PMC8054231
doi:
Substances chimiques
Oxygen
S88TT14065
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
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