Snow White and the Seven Dwarfs: a fairytale for endocrinologists.

dwarfism growth pituitary pseudohypoparathyroidism

Journal

Endocrine connections
ISSN: 2049-3614
Titre abrégé: Endocr Connect
Pays: England
ID NLM: 101598413

Informations de publication

Date de publication:
19 May 2021
Historique:
received: 22 02 2021
accepted: 16 04 2021
pubmed: 21 4 2021
medline: 21 4 2021
entrez: 20 4 2021
Statut: epublish

Résumé

'Snow White and the Seven Dwarfs', a fairytale that is widely known across the Western world, was originally written by the Brothers Grimm, and published in 1812 as 'Snow White'. Though each dwarf was first given an individual name in the 1912 Broadway play, in Walt Disney's 1937 film 'Snow White and the Seven Dwarfs', they were renamed, and the dwarfs have become household names. It is well known that myths, fables, and fairytales, though appearing to be merely children's tales about fictional magical beings and places, have, more often than not, originated from real facts. Therefore, the presence of the seven brothers with short stature in the story is, from an endocrinological point of view, highly intriguing, in fact, thrilling. The diversity of the phenotypes among the seven dwarfs is also stimulating, although puzzling. We undertook a differential diagnosis of their common underlying disorder based on the original Disney production's drawings and the unique characteristics of these little gentlemen, while we additionally evaluated several causes of short stature and, focusing on endocrine disorders that could lead to these clinical features among siblings, we have, we believe, been able to reveal the underlying disease depicted in this archetypal tale.

Identifiants

pubmed: 33878729
doi: 10.1530/EC-20-0615
pii: EC-20-0615
pmc: PMC8183629
doi:
pii:

Types de publication

Journal Article Review

Langues

eng

Pagination

R189-R199

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Auteurs

Athanasios Zervas (A)

Endocrine Unit, Athens Medical Centre, Athens, Greece.

George Chrousos (G)

Division of Endocrinology, Metabolism and Diabetes, First Department of Pediatrics, University Research Institute of Maternal and Child Health and Precision Medicine, and UNESCO Chair on Adolescent Health Care, National and Kapodistrian University of Athens, Athens, Greece.
National and Kapodistrian University of Athens Medical School, 'Aghia Sophia' Children's Hospital, Athens, Greece.

Sarantis Livadas (S)

Endocrine Unit, Athens Medical Centre, Athens, Greece.

Classifications MeSH