The Pharmacology of Two-Pore Domain Potassium Channels.
Background current
K2P channel
KCNK
TALK
TASK
THIK
TRAAK
TREK
TRESK
TWIK
Journal
Handbook of experimental pharmacology
ISSN: 0171-2004
Titre abrégé: Handb Exp Pharmacol
Pays: Germany
ID NLM: 7902231
Informations de publication
Date de publication:
2021
2021
Historique:
pubmed:
22
4
2021
medline:
30
9
2021
entrez:
21
4
2021
Statut:
ppublish
Résumé
Two-pore domain potassium channels are formed by subunits that each contain two pore-loops moieties. Whether the channels are expressed in yeast or the human central nervous system, two subunits come together to form a single potassium selective pore. TOK1, the first two-domain channel was cloned from Saccharomyces cerevisiae in 1995 and soon thereafter, 15 distinct K
Identifiants
pubmed: 33880623
doi: 10.1007/164_2021_462
doi:
Substances chimiques
Potassium Channels, Tandem Pore Domain
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
417-443Subventions
Organisme : NHLBI NIH HHS
ID : R01 HL144615
Pays : United States
Informations de copyright
© 2021. The Author(s), under exclusive license to Springer Nature Switzerland AG.
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