Human Oxygenase Variants Employing a Single Protein Fe


Journal

Angewandte Chemie (International ed. in English)
ISSN: 1521-3773
Titre abrégé: Angew Chem Int Ed Engl
Pays: Germany
ID NLM: 0370543

Informations de publication

Date de publication:
21 06 2021
Historique:
received: 15 03 2021
pubmed: 23 4 2021
medline: 16 9 2021
entrez: 22 4 2021
Statut: ppublish

Résumé

Aspartate/asparagine-β-hydroxylase (AspH) is a human 2-oxoglutarate (2OG) and Fe

Identifiants

pubmed: 33887099
doi: 10.1002/anie.202103711
pmc: PMC8252765
doi:

Substances chimiques

Ferrous Compounds 0
Ligands 0
Aspartic Acid 30KYC7MIAI
Asparagine 7006-34-0
Mixed Function Oxygenases EC 1.-
aspartic acid 2-oxoglutarate-dependent dioxygenase EC 1.14.11.-

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

14657-14663

Subventions

Organisme : Cancer Research UK
ID : C8717/A18245
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/M011224/1
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 106244/Z/14/Z
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/J003018/1
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/R000344/1
Pays : United Kingdom
Organisme : Wellcome Trust
Pays : United Kingdom

Informations de copyright

© 2021 The Authors. Angewandte Chemie International Edition published by Wiley-VCH GmbH.

Références

Nat Commun. 2019 Oct 28;10(1):4910
pubmed: 31659163
Oncotarget. 2015 Jan 20;6(2):1231-48
pubmed: 25483102
Cancer Res. 2000 Mar 1;60(5):1261-6
pubmed: 10728685
Chem Sci. 2020 Dec 7;12(4):1327-1342
pubmed: 34163896
Proc Natl Acad Sci U S A. 1989 May;86(10):3609-13
pubmed: 2726737
Sci Rep. 2020 May 26;10(1):8650
pubmed: 32457455
Genes Dev. 2016 Apr 1;30(7):733-50
pubmed: 27036965
J Theor Biol. 1982 Jan 21;94(2):421-55
pubmed: 6281585
J Biol Chem. 2020 Jun 5;295(23):7826-7838
pubmed: 32107312
Chembiochem. 2012 Jul 23;13(11):1559-63
pubmed: 22730246
J Mol Biol. 2011 Feb 11;406(1):1-8
pubmed: 21167174
Eur J Biochem. 1984 Jan 16;138(2):239-45
pubmed: 6321169
J Biomol Screen. 1999;4(2):67-73
pubmed: 10838414
J Exp Clin Cancer Res. 2020 Aug 18;39(1):163
pubmed: 32811566
J Biol Chem. 2003 Jan 17;278(3):1802-6
pubmed: 12446723
Nat Rev Genet. 2012 Apr 03;13(5):343-57
pubmed: 22473383
J Biol Chem. 2015 Aug 21;290(34):20702-20711
pubmed: 26152721
Biochem J. 1977 Aug 15;166(2):225-35
pubmed: 199159
J Biol Inorg Chem. 2017 Apr;22(2-3):425-452
pubmed: 28124122
Chem Rev. 2013 May 8;113(5):3248-96
pubmed: 23461563
J Biol Chem. 2007 Feb 16;282(7):4524-4532
pubmed: 17182618
Mol Cell. 2008 May 23;30(4):393-402
pubmed: 18498744
J Inorg Biochem. 2017 Jan;166:26-33
pubmed: 27815979
Pharmacol Res. 2011 Sep;64(3):268-73
pubmed: 21504793
Nat Rev Mol Cell Biol. 2004 May;5(5):343-54
pubmed: 15122348
Proc Natl Acad Sci U S A. 1994 Jul 19;91(15):7227-31
pubmed: 8041771
Bioorg Med Chem. 2020 Oct 15;28(20):115675
pubmed: 33069066
Proc Natl Acad Sci U S A. 1989 Jan;86(2):444-7
pubmed: 2492106
Biochemistry. 1996 Apr 2;35(13):3957-62
pubmed: 8672427
J Biol Chem. 2004 Mar 12;279(11):9899-904
pubmed: 14701857
Angew Chem Int Ed Engl. 2021 Jun 21;60(26):14657-14663
pubmed: 33887099
EBioMedicine. 2018 May;31:287-298
pubmed: 29764768
J Clin Invest. 1996 Sep 15;98(6):1313-23
pubmed: 8823296
Biochemistry. 1983 Jun 7;22(12):2875-84
pubmed: 6871167
J Am Chem Soc. 2017 Aug 30;139(34):11980-11988
pubmed: 28780854
Oncol Rep. 2020 Dec;44(6):2364-2372
pubmed: 33125119
Nat Prod Rep. 2018 Aug 15;35(8):792-837
pubmed: 29932179
J Biol Inorg Chem. 2017 Apr;22(2-3):339-365
pubmed: 28074299
J Biol Chem. 1990 May 25;265(15):8558-65
pubmed: 2187868
J Biol Chem. 1983 Oct 25;258(20):12509-12
pubmed: 6630196
Gene. 1994 Dec 15;150(2):395-9
pubmed: 7821814
Nature. 2008 Sep 18;455(7211):333-40
pubmed: 18800132
J Biol Chem. 2008 Sep 19;283(38):25971-8
pubmed: 18611856
FASEB J. 2014 Apr;28(4):1534-42
pubmed: 24334705

Auteurs

Amelia Brasnett (A)

Chemistry Research Laboratory and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK.

Inga Pfeffer (I)

Chemistry Research Laboratory and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK.

Lennart Brewitz (L)

Chemistry Research Laboratory and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK.

Rasheduzzaman Chowdhury (R)

Chemistry Research Laboratory and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK.

Yu Nakashima (Y)

Chemistry Research Laboratory and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK.
Present address: Institute of Natural Medicine, University of Toyama, 2630-Sugitani, 930-0194, Toyama, Japan.

Anthony Tumber (A)

Chemistry Research Laboratory and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK.

Michael A McDonough (MA)

Chemistry Research Laboratory and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK.

Christopher J Schofield (CJ)

Chemistry Research Laboratory and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH