Newly detected rapid eye movement associated sleep apnea after coronavirus disease 2019 as a possible cause for chronic fatigue: two case reports.
APAP
COVID-19
CPAP
Case report
Fatigue syndrome
REM phase
Sleep apnea
Journal
Journal of medical case reports
ISSN: 1752-1947
Titre abrégé: J Med Case Rep
Pays: England
ID NLM: 101293382
Informations de publication
Date de publication:
22 Apr 2021
22 Apr 2021
Historique:
received:
26
11
2020
accepted:
24
03
2021
entrez:
23
4
2021
pubmed:
24
4
2021
medline:
27
4
2021
Statut:
epublish
Résumé
Coronavirus disease 2019 has become a health problem spreading worldwide with pandemic characteristics since March 2020. Post coronavirus disease 2019 symptoms are more frequent than initially expected, with fatigue as an often-mentioned issue. We describe a 32-year-old white male and a 55-year-old white female who suffered from post coronavirus disease 2019 fatigue syndrome. On polysomnography, rapid eye movement associated sleep apnea with an increased hypopnea index during rapid eye movement phases of 36.8 and 19.5 events per hour was found. Based on the patients' burdensome fatigue symptoms, we initiated automatic positive airway pressure therapy, which diminished sleep apnea (rapid eye movement index: 0.0 in both patients) and, consequently, also the fatigue symptoms. Since sleep apnea and coronavirus disease 2019 are both associated with fatigue, a screening for sleep apnea might be considered in coronavirus disease 2019 patients with fatigue syndrome.
Sections du résumé
BACKGROUND
BACKGROUND
Coronavirus disease 2019 has become a health problem spreading worldwide with pandemic characteristics since March 2020. Post coronavirus disease 2019 symptoms are more frequent than initially expected, with fatigue as an often-mentioned issue.
CASE PRESENTATIONS
METHODS
We describe a 32-year-old white male and a 55-year-old white female who suffered from post coronavirus disease 2019 fatigue syndrome. On polysomnography, rapid eye movement associated sleep apnea with an increased hypopnea index during rapid eye movement phases of 36.8 and 19.5 events per hour was found. Based on the patients' burdensome fatigue symptoms, we initiated automatic positive airway pressure therapy, which diminished sleep apnea (rapid eye movement index: 0.0 in both patients) and, consequently, also the fatigue symptoms.
CONCLUSIONS
CONCLUSIONS
Since sleep apnea and coronavirus disease 2019 are both associated with fatigue, a screening for sleep apnea might be considered in coronavirus disease 2019 patients with fatigue syndrome.
Identifiants
pubmed: 33888154
doi: 10.1186/s13256-021-02819-0
pii: 10.1186/s13256-021-02819-0
pmc: PMC8061449
doi:
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
211Références
Eur Neurol. 1986;25 Suppl 2:104-10
pubmed: 3758112
JAMA. 2020 Aug 11;324(6):603-605
pubmed: 32644129
N Engl J Med. 2020 Jun 4;382(23):2268-2270
pubmed: 32294339
Lancet Haematol. 2020 Jun;7(6):e438-e440
pubmed: 32407672
Brain Behav Immun. 2020 Oct;89:543-554
pubmed: 32682993