Clinical features and disease severity in an Iranian population of inpatients with COVID-19.


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
22 04 2021
Historique:
received: 25 07 2020
accepted: 06 04 2021
entrez: 23 4 2021
pubmed: 24 4 2021
medline: 1 5 2021
Statut: epublish

Résumé

Coronavirus disease 2019 (COVID-19) can present with a variety of symptoms. Severity of the disease may be associated with several factors. Here, we review clinical features of COVID-19 inpatients with different severities. This cross-sectional study was performed in Imam Reza hospital, Mashhad, Iran, during February-April 2020. COVID-19 patients with typical computed tomography (CT) patterns and/or positive reverse-transcriptase polymerase chain reaction (RT-PCR) were included. The patients were classified into three groups of moderate, severe, and critical based on disease severity. Demographic, clinical, laboratory, and radiologic findings were collected and compared. P < 0.05 was considered statistically significant. Overall, 200 patients with mean age of 69.75 ± 6.39 years, of whom 82 (41%) were female were studied. Disease was severe/critical in the majority of patients (167, 83.5%). Disease severity was significantly associated with age, malignant comorbidities, dyspnea, nausea/vomiting, confusion, respiratory rate, pulse rate, O

Identifiants

pubmed: 33888747
doi: 10.1038/s41598-021-87917-1
pii: 10.1038/s41598-021-87917-1
pmc: PMC8062510
doi:

Substances chimiques

C-Reactive Protein 9007-41-4

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

8731

Subventions

Organisme : Mashhad University of Medical Sciences
ID : 981800

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Auteurs

Shima Nabavi (S)

Department of Internal Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Zahra Javidarabshahi (Z)

Lung Diseases Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Abolghasem Allahyari (A)

Department of Hematology-Oncology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Mohammad Ramezani (M)

Student Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Mohsen Seddigh-Shamsi (M)

Department of Hematology-Oncology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Sahar Ravanshad (S)

Department of Internal Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Mina AkbariRad (M)

Department of Internal Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Farnoosh Ebrahimzadeh (F)

Department of Internal Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Shohre Khatami (S)

Department of Internal Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Maryam Emadzadeh (M)

Clinical Research Development Unit, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.

Neda Saeedian (N)

Department of Internal Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Ahmadreza Zarifian (A)

Clinical Research Development Unit, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.

Maryam Miri (M)

Kidney Transplantation Complications Research Centre, Mashhad University of Medical Sciences, Mashhad, Iran.

Fariba Rezaeetalab (F)

Lung Diseases Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Sepide Hejazi (S)

Lung Diseases Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Reza Basiri (R)

Lung Diseases Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Mahnaz Mozdourian (M)

Lung Diseases Research Center, Mashhad University of Medical Sciences, Mashhad, Iran. mozdorianmh@mums.ac.ir.

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Classifications MeSH