Detection of the new SARS-CoV-2 variants of concern B.1.1.7 and B.1.351 in five SARS-CoV-2 rapid antigen tests (RATs), Germany, March 2021.
B.1.1.7
B.1.351
Rapid antigen test(s)
SARS-CoV-2
Variant(s) of Concern
performance
Journal
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
ISSN: 1560-7917
Titre abrégé: Euro Surveill
Pays: Sweden
ID NLM: 100887452
Informations de publication
Date de publication:
04 2021
04 2021
Historique:
entrez:
23
4
2021
pubmed:
24
4
2021
medline:
29
4
2021
Statut:
ppublish
Résumé
SARS-CoV-2 variants of concern (VOC) should not escape molecular surveillance. We investigated if SARS-CoV-2 rapid antigen tests (RATs) could detect B.1.1.7 and B.1.351 VOCs in certain laboratory conditions. Infectious cell culture supernatants containing B.1.1.7, B.1.351 or non-VOC SARS-CoV-2 were respectively diluted both in DMEM and saliva. Dilutions were analysed with Roche, Siemens, Abbott, nal von minden and RapiGEN RATs. While further studies with appropriate real-life clinical samples are warranted, all RATs detected B.1.1.7 and B.1.351, generally comparable to non-VOC strain.
Identifiants
pubmed: 33890568
doi: 10.2807/1560-7917.ES.2021.26.16.2100413
pmc: PMC8063588
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Investigateurs
Bernadett Bartha-Dima
(B)
Katja Bengs
(K)
Anja Berger
(A)
Kerstin Boll
(K)
Anja Carl
(A)
Christian Jürgen
(C)
Juliana Drdlicek
(J)
David Eisenberger
(D)
Jennifer Flechsler
(J)
Lars Gerdes
(L)
George Githure
(G)
Janani Govindaswamy
(J)
Christine Hupfer
(C)
Regina Konrad
(R)
Gaia Lupoli
(G)
Johannes Lutmayr
(J)
Gabriele Margos
(G)
Roswitha Müller
(R)
Silke Nickel
(S)
Mercy Okeyo
(M)
Melanie Pavlovic
(M)
Sven Pecoraro
(S)
Isabel Sahm
(I)
Melanie Schauer
(M)
Anika Schülein
(A)
Eva-Maria Schürmann
(EM)
Gesine Schulze
(G)
Nelly Scuda
(N)
Stefanie Singer
(S)
Thorsten Stellberger
(T)
Bianca Treis
(B)
Christian Tuschak
(C)
Pia Zimmermann
(P)
Natali Paravinja
(N)
Commentaires et corrections
Type : ErratumIn
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