Drosophila female reproductive tract gene expression reveals coordinated mating responses and rapidly evolving tissue-specific genes.
ejaculate–female interactions
fertility
reproduction
sexual selection
Journal
G3 (Bethesda, Md.)
ISSN: 2160-1836
Titre abrégé: G3 (Bethesda)
Pays: England
ID NLM: 101566598
Informations de publication
Date de publication:
23 04 2021
23 04 2021
Historique:
received:
07
10
2020
accepted:
29
12
2020
entrez:
23
4
2021
pubmed:
24
4
2021
medline:
7
7
2021
Statut:
ppublish
Résumé
Sexual reproduction in internally fertilizing species requires complex coordination between female and male reproductive systems and among the diverse tissues of the female reproductive tract (FRT). Here, we report a comprehensive, tissue-specific investigation of Drosophila melanogaster FRT gene expression before and after mating. We identified expression profiles that distinguished each tissue, including major differences between tissues with glandular or primarily nonglandular epithelium. All tissues were enriched for distinct sets of genes possessing secretion signals that exhibited accelerated evolution, as might be expected for genes participating in molecular interactions between the sexes within the FRT extracellular environment. Despite robust transcriptional differences between tissues, postmating responses were dominated by coordinated transient changes indicative of an integrated systems-level functional response. This comprehensive characterization of gene expression throughout the FRT identifies putative female contributions to postcopulatory events critical to reproduction and potentially reproductive isolation, as well as the putative targets of sexual selection and conflict.
Identifiants
pubmed: 33890615
pii: 6121924
doi: 10.1093/g3journal/jkab020
pmc: PMC8063083
pii:
doi:
Banques de données
figshare
['10.25387/g3.13503336']
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : NICHD NIH HHS
ID : R21 HD088910
Pays : United States
Informations de copyright
© The Author(s) 2021. Published by Oxford University Press on behalf of Genetics Society of America.
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