Pipeline embolization of distal posterior inferior cerebellar artery aneurysms.


Journal

Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences
ISSN: 2385-2011
Titre abrégé: Interv Neuroradiol
Pays: United States
ID NLM: 9602695

Informations de publication

Date de publication:
Dec 2021
Historique:
pubmed: 25 4 2021
medline: 15 12 2021
entrez: 24 4 2021
Statut: ppublish

Résumé

Flow diversion is commonly used to treat intracranial aneurysms in various regions of the cerebral vasculature, but is only approved for use in the internal carotid arteries. Treatment of distal PICA aneurysms with PED is sometimes performed but has not been well studied. Here, we report our experience with flow diversion of distal PICA aneurysms with PED. Clinical and angiographic data of eligible patients was retrospectively obtained and assessed for key demographic characteristics and clinical and angiographic outcomes. Principal outcomes included rates of aneurysm occlusion, ischemic or hemorrhagic complication, technical complication, and in-stent stenosis. Three female and 2 male patients underwent placement of PED in the PICA for treatment of 5 distal PICA aneurysms. Clinical and angiographic follow-up was obtained for all patients. Complete aneurysm occlusion was observed in 100% (5/5) of treated aneurysms at 6 month and longest angiographic follow-up. While there were no ischemic or device-related complications, delayed hemorrhagic complications occurred in 20% (1/5) of patients. Pipeline embolization of distal PICA aneurysms can be performed in select patients. Further study is necessary in larger cohorts to better define clinical scenarios in which flow diversion in the distal PICA should be considered.

Sections du résumé

BACKGROUND AND PURPOSE OBJECTIVE
Flow diversion is commonly used to treat intracranial aneurysms in various regions of the cerebral vasculature, but is only approved for use in the internal carotid arteries. Treatment of distal PICA aneurysms with PED is sometimes performed but has not been well studied. Here, we report our experience with flow diversion of distal PICA aneurysms with PED.
MATERIALS AND METHODS METHODS
Clinical and angiographic data of eligible patients was retrospectively obtained and assessed for key demographic characteristics and clinical and angiographic outcomes. Principal outcomes included rates of aneurysm occlusion, ischemic or hemorrhagic complication, technical complication, and in-stent stenosis.
RESULTS RESULTS
Three female and 2 male patients underwent placement of PED in the PICA for treatment of 5 distal PICA aneurysms. Clinical and angiographic follow-up was obtained for all patients. Complete aneurysm occlusion was observed in 100% (5/5) of treated aneurysms at 6 month and longest angiographic follow-up. While there were no ischemic or device-related complications, delayed hemorrhagic complications occurred in 20% (1/5) of patients.
CONCLUSION CONCLUSIONS
Pipeline embolization of distal PICA aneurysms can be performed in select patients. Further study is necessary in larger cohorts to better define clinical scenarios in which flow diversion in the distal PICA should be considered.

Identifiants

pubmed: 33892602
doi: 10.1177/15910199211013195
pmc: PMC8673893
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

821-827

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Auteurs

David C Lauzier (DC)

Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA.

Brandon K Root (BK)

Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA.

Yasha Kayan (Y)

Division of Neurointerventional Radiology, Neuroscience Institute, Abbott Northwestern Hospital, Minneapolis, MN, USA.

Josser E Delgado Almandoz (JED)

Division of Neurointerventional Radiology, Neuroscience Institute, Abbott Northwestern Hospital, Minneapolis, MN, USA.

Joshua W Osbun (JW)

Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA.
Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.
Department of Neurological Surgery, Washington University School of Medicine, St. Louis, MO, USA.

Arindam R Chatterjee (AR)

Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA.
Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.
Department of Neurological Surgery, Washington University School of Medicine, St. Louis, MO, USA.

Kayla L Whaley (KL)

Neuroscience Institute, Abbott Northwestern Hospital, Minneapolis, MN, USA.

Megan E Tipps (ME)

Neuroscience Institute, Abbott Northwestern Hospital, Minneapolis, MN, USA.

Christopher J Moran (CJ)

Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA.
Department of Neurological Surgery, Washington University School of Medicine, St. Louis, MO, USA.

Akash P Kansagra (AP)

Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA.
Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.
Department of Neurological Surgery, Washington University School of Medicine, St. Louis, MO, USA.

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