Nonpharmacologic Treatments for Opioid Reduction in Patients With Advanced Chronic Kidney Disease.


Journal

Seminars in nephrology
ISSN: 1558-4488
Titre abrégé: Semin Nephrol
Pays: United States
ID NLM: 8110298

Informations de publication

Date de publication:
01 2021
Historique:
entrez: 26 4 2021
pubmed: 27 4 2021
medline: 15 12 2021
Statut: ppublish

Résumé

Opioid analgesics carry risk for serious health-related harms in patients with advanced chronic kidney disease (CKD) and end-stage kidney disease. In the general population with chronic noncancer pain, there is some evidence that opioid reduction or discontinuation is associated with improved pain outcomes; however, tapering opioids abruptly or without providing supportive interventions can lead to physical and psychological harms and relapse of opioid use. There is emerging evidence that nonpharmacologic treatments such as psychosocial interventions, acupuncture, and interdisciplinary pain management programs are effective approaches to support opioid dose reduction in patients experiencing persistent pain, but research in this area still is relatively new. This review describes the current evidence for nonpharmacologic interventions to support opioid reduction in non-CKD patients with pain and discusses the application of the available evidence to patients with advanced CKD who are prescribed opioids to manage pain.

Identifiants

pubmed: 33896475
pii: S0270-9295(21)00025-5
doi: 10.1016/j.semnephrol.2021.02.007
pmc: PMC9366727
mid: NIHMS1672876
pii:
doi:

Substances chimiques

Analgesics, Opioid 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

68-81

Subventions

Organisme : NIDDK NIH HHS
ID : U01 DK123813
Pays : United States
Organisme : NIDDK NIH HHS
ID : U01 DK123821
Pays : United States
Organisme : NIDDK NIH HHS
ID : U01 DK123817
Pays : United States
Organisme : NCCIH NIH HHS
ID : K23 AT009208
Pays : United States
Organisme : NIDDK NIH HHS
ID : U01 DK123786
Pays : United States
Organisme : NIDDK NIH HHS
ID : U01 DK123814
Pays : United States
Organisme : NIDDK NIH HHS
ID : U01 DK123812
Pays : United States

Informations de copyright

Copyright © 2021 Elsevier Inc. All rights reserved.

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Auteurs

Carrie E Brintz (CE)

Division of Pain Medicine, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville, TN. Electronic address: carrie.brintz@vumc.org.

Martin D Cheatle (MD)

Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.

Laura M Dember (LM)

Renal, Electrolyte and Hypertension Division, Department of Medicine, University of Pennsylvania, Philadelphia, PA; Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.

Alicia A Heapy (AA)

Pain Research Informatics Multimorbidities and Education Center of Innovation, Veterans' Affairs Connecticut Healthcare System, West Haven, CT; Department of Psychiatry, Yale School of Medicine, New Haven, CT.

Manisha Jhamb (M)

Renal-Electrolyte Division, Department of Medicine, University of Pittsburgh, Pittsburgh, PA.

Amanda J Shallcross (AJ)

Department of Population Health, New York University School of Medicine, New York, NY.

Jennifer L Steel (JL)

Department of Surgery, University of Pittsburgh, Pittsburgh, PA; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA; Department of Psychology, University of Pittsburgh, Pittsburgh, PA; Behavioral Health, The Rogosin Institute, New York, NY.

Paul L Kimmel (PL)

National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD.

Daniel Cukor (D)

Behavioral Health, The Rogosin Institute, New York, NY.

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Classifications MeSH