Plasma Metabolome Signature Indicative of

BRCA1 germline mutation HIF1 alpha NAD+ balance aerobic glycolysis breast cancer energy metabolism lactate plasma metabolome

Journal

Frontiers in oncology
ISSN: 2234-943X
Titre abrégé: Front Oncol
Pays: Switzerland
ID NLM: 101568867

Informations de publication

Date de publication:
2021
Historique:
received: 08 11 2020
accepted: 19 01 2021
entrez: 26 4 2021
pubmed: 27 4 2021
medline: 27 4 2021
Statut: epublish

Résumé

Individuals carrying a pathogenic germline variant in the breast cancer predisposition gene

Identifiants

pubmed: 33898308
doi: 10.3389/fonc.2021.627217
pmc: PMC8058469
doi:

Types de publication

Journal Article

Langues

eng

Pagination

627217

Informations de copyright

Copyright © 2021 Penkert, Märtens, Seifert, Auber, Derlin, Hille-Betz, Hörmann, Klopp, Prokein, Schlicker, Wacker, Wallaschek, Schlegelberger, Hiller, Ripperger and Illig.

Déclaration de conflit d'intérêts

MS was employed by the company Connexome Consulting. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Judith Penkert (J)

Department of Human Genetics, Hannover Medical School, Hannover, Germany.

Andre Märtens (A)

Department of Bioinformatics and Biochemistry, Braunschweig Integrated Center of Systems Biology (BRICS), Technische Universität Braunschweig, Braunschweig, Germany.

Martin Seifert (M)

Connexome Consulting, Fischen, Germany.

Bernd Auber (B)

Department of Human Genetics, Hannover Medical School, Hannover, Germany.

Katja Derlin (K)

Department of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.

Ursula Hille-Betz (U)

Department of Obstetrics and Gynecology, Hannover Medical School, Hannover, Germany.

Philipp Hörmann (P)

Department of Bioinformatics and Biochemistry, Braunschweig Integrated Center of Systems Biology (BRICS), Technische Universität Braunschweig, Braunschweig, Germany.

Norman Klopp (N)

Hannover Unified Biobank (HUB), Hannover, Germany.

Jana Prokein (J)

Center for Information Management, Hannover Medical School, Hannover, Germany.

Lisa Schlicker (L)

Division of Tumour Metabolism and Microenvironment, German Cancer Research Center (DKFZ), Heidelberg, Germany.

Frank Wacker (F)

Department of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.

Hannah Wallaschek (H)

Department of Human Genetics, Hannover Medical School, Hannover, Germany.

Brigitte Schlegelberger (B)

Department of Human Genetics, Hannover Medical School, Hannover, Germany.

Karsten Hiller (K)

Department of Bioinformatics and Biochemistry, Braunschweig Integrated Center of Systems Biology (BRICS), Technische Universität Braunschweig, Braunschweig, Germany.
Computational Biology of Infection Research, Helmholtz Centre for Infection Research, Braunschweig, Germany.

Tim Ripperger (T)

Department of Human Genetics, Hannover Medical School, Hannover, Germany.

Thomas Illig (T)

Department of Human Genetics, Hannover Medical School, Hannover, Germany.
Hannover Unified Biobank (HUB), Hannover, Germany.

Classifications MeSH