Generation of two additional integration-free iPSC lines from related human donors.
Differentiation
Multi-Organ-Chips
Organ-on-a-chip
Stem cells
iPSCs
induced pluripotent stem cells
Journal
Stem cell research
ISSN: 1876-7753
Titre abrégé: Stem Cell Res
Pays: England
ID NLM: 101316957
Informations de publication
Date de publication:
05 2021
05 2021
Historique:
received:
02
03
2021
revised:
25
03
2021
accepted:
29
03
2021
pubmed:
27
4
2021
medline:
1
7
2021
entrez:
26
4
2021
Statut:
ppublish
Résumé
The integration-free iPSC lines TISSUi006-A and TISSUi007-A were generated by reprogramming blood cells with episomal vectors. The male human donors belong to a Caucasian family in which four additional family members donated and iPSC lines were generated. All iPSC lines within this family are approved for commercial use by donor consent. Those iPSC lines offer the opportunity to study the influence of affiliation within one family. In future, more iPSCs lines of many more family members can be created to understand the effects of relatives with different ages on the reprogramming into iPSCs and differentiation into specific cell types.
Identifiants
pubmed: 33901815
pii: S1873-5061(21)00173-2
doi: 10.1016/j.scr.2021.102327
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
102327Informations de copyright
Copyright © 2021 The Authors. Published by Elsevier B.V. All rights reserved.