Human dental pulp stem cell responses to different dental pulp capping materials.
Calcium hydroxide
Calcium silicate materials
Human dental pulp cells
Mineral trioxide aggregate
Pulp capping
Journal
BMC oral health
ISSN: 1472-6831
Titre abrégé: BMC Oral Health
Pays: England
ID NLM: 101088684
Informations de publication
Date de publication:
26 04 2021
26 04 2021
Historique:
received:
16
12
2020
accepted:
01
04
2021
entrez:
27
4
2021
pubmed:
28
4
2021
medline:
5
6
2021
Statut:
epublish
Résumé
Direct pulp capping is a vital pulp therapy for a pin-point dental pulp exposure. Applying a pulp capping material leads to the formation of a dentin bridge and protects pulp vitality. The aim of this study was to compare the effects of four dental materials, DyCal Human dental pulp stem cells (hDPs) were isolated and characterized. Extraction medium was prepared from the different pulp capping materials. The hDP cytotoxicity, proliferation, and migration were examined. The odonto/osteogenic differentiation was determined by alkaline phosphatase, Von Kossa, and alizarin red s staining. Osteogenic marker gene expression was evaluated using real-time polymerase chain reaction. ProRoot This study demonstrates the favorable in vitro biocompatibility and bioactive properties of ProRoot
Sections du résumé
BACKGROUND
Direct pulp capping is a vital pulp therapy for a pin-point dental pulp exposure. Applying a pulp capping material leads to the formation of a dentin bridge and protects pulp vitality. The aim of this study was to compare the effects of four dental materials, DyCal
METHODS
Human dental pulp stem cells (hDPs) were isolated and characterized. Extraction medium was prepared from the different pulp capping materials. The hDP cytotoxicity, proliferation, and migration were examined. The odonto/osteogenic differentiation was determined by alkaline phosphatase, Von Kossa, and alizarin red s staining. Osteogenic marker gene expression was evaluated using real-time polymerase chain reaction.
RESULTS
ProRoot
CONCLUSION
This study demonstrates the favorable in vitro biocompatibility and bioactive properties of ProRoot
Identifiants
pubmed: 33902558
doi: 10.1186/s12903-021-01544-w
pii: 10.1186/s12903-021-01544-w
pmc: PMC8074430
doi:
Substances chimiques
Aluminum Compounds
0
Calcium Compounds
0
Drug Combinations
0
Oxides
0
Pulp Capping and Pulpectomy Agents
0
Silicates
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
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