[Sexual and physical abuse during childhood; what is the impact on outcome in first episode psychosis patients?]
Traumatisme sexuel ou physique dans l’enfance : quel impact sur l’évolution d’un premier épisode psychotique ?
Abus physique
Abus sexuel
Early intervention
Intervention précoce
Physical abuse
Prognosis
Pronostic
Psychose
Psychosis
Sexual abuse
Trauma
Journal
L'Encephale
ISSN: 0013-7006
Titre abrégé: Encephale
Pays: France
ID NLM: 7505643
Informations de publication
Date de publication:
Jun 2021
Jun 2021
Historique:
received:
29
11
2019
revised:
08
06
2020
accepted:
19
06
2020
pubmed:
28
4
2021
medline:
25
11
2021
entrez:
27
4
2021
Statut:
ppublish
Résumé
If exposure to childhood trauma increases the risk to later develop a psychotic disorder, the impact of such events on clinical presentation and outcome after a first psychotic episode deserves attention both in order to identify specific patients' needs and to develop adapted therapeutic interventions. Three hundred and sixty-two patients treated at TIPP-Lausanne, a specialized program for the treatment of the early phase of psychotic disorders, were assessed prospectively, from baseline and every six months until the end of the 36 months of treatment. We compared characteristics of patients exposed to childhood sexual and/or physical abuse to those of non-exposed patients. One hundred and eight patients (29.8 %) were exposed to at least one episode of physical and/or sexual abuse during childhood. Exposed patients displayed higher levels of positive and depressive symptoms and had lower levels of functioning throughout the entire three year follow-up period. The prevalence of exposure to major traumatic events during childhood in early psychosis patients is very high, and it has an important impact on symptomatic and functional outcome. However, when clinical care is adapted, such patients seem to have a great potential for recovery. This justifies the implementation of specialized early psychosis programs and additional research in order to develop specific and adapted therapeutic strategies for such patients.
Sections du résumé
BACKGROUND
BACKGROUND
If exposure to childhood trauma increases the risk to later develop a psychotic disorder, the impact of such events on clinical presentation and outcome after a first psychotic episode deserves attention both in order to identify specific patients' needs and to develop adapted therapeutic interventions.
METHODS
METHODS
Three hundred and sixty-two patients treated at TIPP-Lausanne, a specialized program for the treatment of the early phase of psychotic disorders, were assessed prospectively, from baseline and every six months until the end of the 36 months of treatment. We compared characteristics of patients exposed to childhood sexual and/or physical abuse to those of non-exposed patients.
RESULTS
RESULTS
One hundred and eight patients (29.8 %) were exposed to at least one episode of physical and/or sexual abuse during childhood. Exposed patients displayed higher levels of positive and depressive symptoms and had lower levels of functioning throughout the entire three year follow-up period.
CONCLUSIONS
CONCLUSIONS
The prevalence of exposure to major traumatic events during childhood in early psychosis patients is very high, and it has an important impact on symptomatic and functional outcome. However, when clinical care is adapted, such patients seem to have a great potential for recovery. This justifies the implementation of specialized early psychosis programs and additional research in order to develop specific and adapted therapeutic strategies for such patients.
Identifiants
pubmed: 33902898
pii: S0013-7006(20)30199-8
doi: 10.1016/j.encep.2020.06.010
pii:
doi:
Types de publication
Journal Article
Langues
fre
Sous-ensembles de citation
IM
Pagination
215-220Informations de copyright
Copyright © 2020 L'Encéphale, Paris. Published by Elsevier Masson SAS. All rights reserved.