Reshaping of the gastrointestinal microbiome alters atherosclerotic plaque inflammation resolution in mice.
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
26 04 2021
26 04 2021
Historique:
received:
24
11
2020
accepted:
13
04
2021
entrez:
27
4
2021
pubmed:
28
4
2021
medline:
11
11
2021
Statut:
epublish
Résumé
Since alterations in the intestinal microbiota may induce systemic inflammation and polarization of macrophages to the M1 state, the microbiome role in atherosclerosis, an M1-driven disease, requires evaluation. We aimed to determine if antibiotic (Abx) induced alterations to the intestinal microbiota interferes with atherosclerotic plaque inflammation resolution after lipid-lowering in mice. Hyperlipidemic Apoe
Identifiants
pubmed: 33903700
doi: 10.1038/s41598-021-88479-y
pii: 10.1038/s41598-021-88479-y
pmc: PMC8076321
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
8966Subventions
Organisme : NIH HHS
ID : R01 HL084312
Pays : United States
Organisme : NHLBI NIH HHS
ID : K23 HL152013
Pays : United States
Références
Atherosclerosis. 2013 Mar;227(1):125-9
pubmed: 23332773
Circulation. 2011 Nov 29;124(22):2458-73
pubmed: 22052934
Circulation. 2013 Nov 26;128(22):2422-46
pubmed: 24166575
J Intern Med. 2010 Oct;268(4):320-8
pubmed: 21050286
Arterioscler Thromb Vasc Biol. 2016 Feb;36(2):226-35
pubmed: 26681754
ISME J. 2012 Aug;6(8):1621-4
pubmed: 22402401
Front Microbiol. 2016 Jul 11;7:1081
pubmed: 27462309
Nat Commun. 2015 Jun 30;6:7486
pubmed: 26123276
MD Comput. 1997 Jul-Aug;14(4):306-17
pubmed: 9230594
Proc Natl Acad Sci U S A. 2010 Apr 6;107(14):6125-6
pubmed: 20360554
Nat Methods. 2016 Jul;13(7):581-3
pubmed: 27214047
Arch Intern Med. 2006 Jan 9;166(1):71-8
pubmed: 16401813
Sci Rep. 2016 Jul 07;6:29353
pubmed: 27383250
J Atheroscler Thromb. 2017 Feb 1;24(2):110-119
pubmed: 27928097
Circ Res. 2020 Jul 31;127(4):553-570
pubmed: 32762536
Nutrients. 2018 Oct 01;10(10):
pubmed: 30275434
Mol Metab. 2020 Jun;36:100976
pubmed: 32251665
Circ Res. 2017 Mar 31;120(7):1183-1196
pubmed: 28360349
Front Microbiol. 2015 Jun 30;6:671
pubmed: 26175728
Front Microbiol. 2014 Apr 29;5:190
pubmed: 24808896
J Clin Invest. 2017 Aug 1;127(8):2904-2915
pubmed: 28650342
Gut. 2018 Sep;67(9):1716-1725
pubmed: 29934437
Gut Microbes. 2012 Jul-Aug;3(4):279-88
pubmed: 22572877
Front Cardiovasc Med. 2018 May 11;5:32
pubmed: 29868610
Bioinformatics. 2011 Apr 15;27(8):1159-61
pubmed: 21349862
PLoS One. 2012;7(6):e39790
pubmed: 22761902
Open Heart. 2019 Apr 23;6(1):e000993
pubmed: 31168383
Arterioscler Thromb Vasc Biol. 2020 Jan;40(1):20-33
pubmed: 31722535
Cardiovasc Res. 2021 Feb 10;:
pubmed: 33576385
J Am Coll Cardiol. 2016 Jun 7;67(22):2620-8
pubmed: 27256833
Nat Commun. 2017 Sep 11;8(1):518
pubmed: 28894149
Front Immunol. 2018 Mar 13;9:302
pubmed: 29593707
Appl Environ Microbiol. 2005 Dec;71(12):8228-35
pubmed: 16332807
BMC Microbiol. 2016 Nov 8;16(1):264
pubmed: 27821063
J Surg Res. 2003 May 15;111(2):171-6
pubmed: 12850459
Genome Res. 2009 Dec;19(12):2317-23
pubmed: 19819907
Genome Med. 2015 Mar 31;7(1):33
pubmed: 25825594
Eur J Clin Invest. 2004 May;34(5):328-34
pubmed: 15147329
Sci Rep. 2019 Sep 9;9(1):12918
pubmed: 31501492
Mol Pharmacol. 2021 Mar;99(3):175-183
pubmed: 33384285
J Am Heart Assoc. 2018 Oct 16;7(20):e009778
pubmed: 30371276
Methods Mol Biol. 2013;1027:123-35
pubmed: 23912984
Front Immunol. 2019 May 24;10:1084
pubmed: 31178859
Lancet. 2010 Nov 13;376(9753):1670-81
pubmed: 21067804