Social support and hippocampal volume are negatively associated in adults with previous experience of childhood maltreatment.

Adult Child Child Abuse Female Hippocampus / anatomy & histology Humans Male Organ Size Protective Factors Social Support / statistics & numerical data

Journal

Journal of psychiatry & neuroscience : JPN
ISSN: 1488-2434
Titre abrégé: J Psychiatry Neurosci
Pays: Canada
ID NLM: 9107859

Informations de publication

Date de publication:
27 04 2021
Historique:
entrez: 27 4 2021
pubmed: 28 4 2021
medline: 27 1 2022
Statut: epublish

Résumé

Childhood maltreatment has been associated with reduced hippocampal volume in healthy individuals, whereas social support, a protective factor, has been positively associated with hippocampal volumes. In this study, we investigated how social support is associated with hippocampal volume in healthy people with previous experience of childhood maltreatment. We separated a sample of 446 healthy participants into 2 groups using the Childhood Trauma Questionnaire: 265 people without maltreatment and 181 people with maltreatment. We measured perceived social support using a short version of the Social Support Questionnaire. We examined hippocampal volume using automated segmentation (Freesurfer). We conducted a social support × group analysis of covariance on hippocampal volumes controlling for age, sex, total intracranial volume, site and verbal intelligence. Our analysis revealed significantly lower left hippocampal volume in people with maltreatment (left F1,432 = 5.686, p = 0.018; right F1,433 = 3.371, p = 0.07), but no main effect of social support emerged. However, we did find a significant social support × group interaction for left hippocampal volume (left F1,432 = 5.712, p = 0.017; right F1,433 = 3.480, p = 0.06). In people without maltreatment, we observed a trend toward a positive association between social support and hippocampal volume. In contrast, social support was negatively associated with hippocampal volume in people with maltreatment. Because of the correlative nature of our study, we could not infer causal relationships between social support, maltreatment and hippocampal volume. Our results point to a complex dynamic between environmental risk, protective factors and brain structure - in line with previous evidence - suggesting a detrimental effect of maltreatment on hippocampal development.

Sections du résumé

Background
Childhood maltreatment has been associated with reduced hippocampal volume in healthy individuals, whereas social support, a protective factor, has been positively associated with hippocampal volumes. In this study, we investigated how social support is associated with hippocampal volume in healthy people with previous experience of childhood maltreatment.
Methods
We separated a sample of 446 healthy participants into 2 groups using the Childhood Trauma Questionnaire: 265 people without maltreatment and 181 people with maltreatment. We measured perceived social support using a short version of the Social Support Questionnaire. We examined hippocampal volume using automated segmentation (Freesurfer). We conducted a social support × group analysis of covariance on hippocampal volumes controlling for age, sex, total intracranial volume, site and verbal intelligence.
Results
Our analysis revealed significantly lower left hippocampal volume in people with maltreatment (left F1,432 = 5.686, p = 0.018; right F1,433 = 3.371, p = 0.07), but no main effect of social support emerged. However, we did find a significant social support × group interaction for left hippocampal volume (left F1,432 = 5.712, p = 0.017; right F1,433 = 3.480, p = 0.06). In people without maltreatment, we observed a trend toward a positive association between social support and hippocampal volume. In contrast, social support was negatively associated with hippocampal volume in people with maltreatment.
Limitations
Because of the correlative nature of our study, we could not infer causal relationships between social support, maltreatment and hippocampal volume.
Conclusion
Our results point to a complex dynamic between environmental risk, protective factors and brain structure - in line with previous evidence - suggesting a detrimental effect of maltreatment on hippocampal development.

Identifiants

DOI: 10.1503/jpn.200162 PMID: 33904668 PMC: PMC8327979
pubmed: 33904668
doi: 10.1503/jpn.200162
pmc: PMC8327979
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

E328-E336

Informations de copyright

© 2021 CMA Joule Inc. or its licensors.

Déclaration de conflit d'intérêts

None declared.

Références

Lancet Psychiatry. 2019 Apr;6(4):318-326
pubmed: 30904126
Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):19119-24
pubmed: 24191026
Neuropsychologia. 2016 May;85:237-44
pubmed: 27039164
Neuropsychopharmacology. 2018 Feb;43(3):546-554
pubmed: 29039414
Soc Psychiatry Psychiatr Epidemiol. 2018 May;53(5):453-475
pubmed: 29349479
Biol Psychiatry. 2010 Feb 15;67(4):357-64
pubmed: 20015483
JAMA Netw Open. 2019 Sep 4;2(9):e1911426
pubmed: 31532514
Depress Anxiety. 1999;9(4):169-74
pubmed: 10431682
Br J Psychiatry Suppl. 1992 Feb;(15):18-23
pubmed: 1389022
Neuroimage. 2010 Jan 1;49(1):1144-50
pubmed: 19595774
Psychol Bull. 1985 Sep;98(2):310-57
pubmed: 3901065
Am J Psychiatry. 1994 Aug;151(8):1132-6
pubmed: 8037246
Behav Res Ther. 2019 Jul;118:101-109
pubmed: 31030002
Cereb Cortex. 2015 Aug;25(8):2204-12
pubmed: 24591525
J Psychiatr Res. 2007 Aug;41(5):435-45
pubmed: 16445942
Psychother Psychosom Med Psychol. 2010 Nov;60(11):442-50
pubmed: 20200804
Depress Anxiety. 2012 May;29(5):449-59
pubmed: 22553009
Child Abuse Negl. 2012 May;36(5):393-403
pubmed: 22609072
Depress Anxiety. 2014 Oct;31(10):880-892
pubmed: 25132653
J Abnorm Psychol. 2003 Aug;112(3):323-38
pubmed: 12943012
Am J Psychiatry. 2020 Jan 1;177(1):37-46
pubmed: 31416339
Biol Psychiatry. 2012 Feb 15;71(4):286-93
pubmed: 22112927
Neuroimage. 2018 May 15;172:450-460
pubmed: 29410079
Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):2854-9
pubmed: 22308421
Psychol Med. 2018 Oct;48(14):2391-2398
pubmed: 29415775
Proc Natl Acad Sci U S A. 2020 Jan 7;117(1):641-649
pubmed: 31907309
Nat Rev Neurosci. 2009 Jun;10(6):434-45
pubmed: 19401723
Child Abuse Negl. 2003 Feb;27(2):169-90
pubmed: 12615092
Neuroimage. 2006 Jul 1;31(3):968-80
pubmed: 16530430
Neurosci Biobehav Rev. 2003 Jan-Mar;27(1-2):33-44
pubmed: 12732221
Nat Rev Neurosci. 2016 Sep 19;17(10):652-66
pubmed: 27640984
Neuron. 2016 Mar 2;89(5):892-909
pubmed: 26938439
Biol Psychiatry. 2000 Oct 15;48(8):755-65
pubmed: 11063972
Child Maltreat. 2009 May;14(2):148-56
pubmed: 18988860
AJNR Am J Neuroradiol. 1999 Apr;20(4):717-23
pubmed: 10319988
J Psychiatry Neurosci. 2011 Jan;36(1):15-22
pubmed: 20964952
Nature. 2018 Mar 15;555(7696):377-381
pubmed: 29513649
Hum Brain Mapp. 2013 Nov;34(11):2899-909
pubmed: 22696400
J Am Acad Child Adolesc Psychiatry. 2013 Apr;52(4):346-58
pubmed: 23582866
Neuropsychologia. 2011 Mar;49(4):651-6
pubmed: 20813118
Am J Med. 1999 Oct;107(4):332-9
pubmed: 10527034
Soc Neurosci. 2014;9(2):152-9
pubmed: 24397344
Eur Arch Psychiatry Clin Neurosci. 2019 Dec;269(8):949-962
pubmed: 30267149
Neuropsychopharmacology. 2014 Nov;39(12):2723-31
pubmed: 24924799
Psychother Psychosom Med Psychol. 2005 May;55(5):266-77
pubmed: 15875274
Child Abuse Negl. 2000 Jun;24(6):781-97
pubmed: 10888018
J Child Psychol Psychiatry. 2016 Mar;57(3):241-66
pubmed: 26831814
Proc Natl Acad Sci U S A. 2016 May 17;113(20):5742-7
pubmed: 27114522
Proc Natl Acad Sci U S A. 1984 Oct;81(19):6174-7
pubmed: 6592609
Psychosom Med. 1976 Sep-Oct;38(5):300-14
pubmed: 981490
Mol Psychiatry. 2011 Mar;16(3):252-64
pubmed: 20661246

Auteurs

Katharina Förster (K)

From the Department of Psychiatry, University of Münster, Münster, Germany (Förster, Danzer, Redlich, Opel, Grotegerd, Leehr, Dohm, Enneking, Meinert, Goltermann, Lemke, Waltemate, Thiel, Behnert, Hahn, Repple, Dannlowski); the Clinical Psychology and Behavioral Neuroscience, Faculty of Psychology, TU Dresden, Dresden, Germany (Förster); the Department of Clinical Psychology, University of Halle, Halle, Germany (Redlich); the Department of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany (Brosch, Stein, Meller, Ringwald, Schmitt, Steinsträter, Jansen, Krug, Nenadic, Kircher); the Core-Unit Brain Imaging, Faculty of Medicine, University of Marburg, Marburg, Germany (Jansen); the Department of Psychiatry, University of Bonn, Bonn, Germany (Krug); and the University Clinic for Clinical Radiology, University of Münster, Münster, Germany (Kugel, Heindel).

Lorenz Danzer (L)

From the Department of Psychiatry, University of Münster, Münster, Germany (Förster, Danzer, Redlich, Opel, Grotegerd, Leehr, Dohm, Enneking, Meinert, Goltermann, Lemke, Waltemate, Thiel, Behnert, Hahn, Repple, Dannlowski); the Clinical Psychology and Behavioral Neuroscience, Faculty of Psychology, TU Dresden, Dresden, Germany (Förster); the Department of Clinical Psychology, University of Halle, Halle, Germany (Redlich); the Department of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany (Brosch, Stein, Meller, Ringwald, Schmitt, Steinsträter, Jansen, Krug, Nenadic, Kircher); the Core-Unit Brain Imaging, Faculty of Medicine, University of Marburg, Marburg, Germany (Jansen); the Department of Psychiatry, University of Bonn, Bonn, Germany (Krug); and the University Clinic for Clinical Radiology, University of Münster, Münster, Germany (Kugel, Heindel).

Ronny Redlich (R)

From the Department of Psychiatry, University of Münster, Münster, Germany (Förster, Danzer, Redlich, Opel, Grotegerd, Leehr, Dohm, Enneking, Meinert, Goltermann, Lemke, Waltemate, Thiel, Behnert, Hahn, Repple, Dannlowski); the Clinical Psychology and Behavioral Neuroscience, Faculty of Psychology, TU Dresden, Dresden, Germany (Förster); the Department of Clinical Psychology, University of Halle, Halle, Germany (Redlich); the Department of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany (Brosch, Stein, Meller, Ringwald, Schmitt, Steinsträter, Jansen, Krug, Nenadic, Kircher); the Core-Unit Brain Imaging, Faculty of Medicine, University of Marburg, Marburg, Germany (Jansen); the Department of Psychiatry, University of Bonn, Bonn, Germany (Krug); and the University Clinic for Clinical Radiology, University of Münster, Münster, Germany (Kugel, Heindel).

Nils Opel (N)

From the Department of Psychiatry, University of Münster, Münster, Germany (Förster, Danzer, Redlich, Opel, Grotegerd, Leehr, Dohm, Enneking, Meinert, Goltermann, Lemke, Waltemate, Thiel, Behnert, Hahn, Repple, Dannlowski); the Clinical Psychology and Behavioral Neuroscience, Faculty of Psychology, TU Dresden, Dresden, Germany (Förster); the Department of Clinical Psychology, University of Halle, Halle, Germany (Redlich); the Department of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany (Brosch, Stein, Meller, Ringwald, Schmitt, Steinsträter, Jansen, Krug, Nenadic, Kircher); the Core-Unit Brain Imaging, Faculty of Medicine, University of Marburg, Marburg, Germany (Jansen); the Department of Psychiatry, University of Bonn, Bonn, Germany (Krug); and the University Clinic for Clinical Radiology, University of Münster, Münster, Germany (Kugel, Heindel).

Dominik Grotegerd (D)

From the Department of Psychiatry, University of Münster, Münster, Germany (Förster, Danzer, Redlich, Opel, Grotegerd, Leehr, Dohm, Enneking, Meinert, Goltermann, Lemke, Waltemate, Thiel, Behnert, Hahn, Repple, Dannlowski); the Clinical Psychology and Behavioral Neuroscience, Faculty of Psychology, TU Dresden, Dresden, Germany (Förster); the Department of Clinical Psychology, University of Halle, Halle, Germany (Redlich); the Department of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany (Brosch, Stein, Meller, Ringwald, Schmitt, Steinsträter, Jansen, Krug, Nenadic, Kircher); the Core-Unit Brain Imaging, Faculty of Medicine, University of Marburg, Marburg, Germany (Jansen); the Department of Psychiatry, University of Bonn, Bonn, Germany (Krug); and the University Clinic for Clinical Radiology, University of Münster, Münster, Germany (Kugel, Heindel).

Elisabeth J Leehr (EJ)

From the Department of Psychiatry, University of Münster, Münster, Germany (Förster, Danzer, Redlich, Opel, Grotegerd, Leehr, Dohm, Enneking, Meinert, Goltermann, Lemke, Waltemate, Thiel, Behnert, Hahn, Repple, Dannlowski); the Clinical Psychology and Behavioral Neuroscience, Faculty of Psychology, TU Dresden, Dresden, Germany (Förster); the Department of Clinical Psychology, University of Halle, Halle, Germany (Redlich); the Department of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany (Brosch, Stein, Meller, Ringwald, Schmitt, Steinsträter, Jansen, Krug, Nenadic, Kircher); the Core-Unit Brain Imaging, Faculty of Medicine, University of Marburg, Marburg, Germany (Jansen); the Department of Psychiatry, University of Bonn, Bonn, Germany (Krug); and the University Clinic for Clinical Radiology, University of Münster, Münster, Germany (Kugel, Heindel).

Katharina Dohm (K)

From the Department of Psychiatry, University of Münster, Münster, Germany (Förster, Danzer, Redlich, Opel, Grotegerd, Leehr, Dohm, Enneking, Meinert, Goltermann, Lemke, Waltemate, Thiel, Behnert, Hahn, Repple, Dannlowski); the Clinical Psychology and Behavioral Neuroscience, Faculty of Psychology, TU Dresden, Dresden, Germany (Förster); the Department of Clinical Psychology, University of Halle, Halle, Germany (Redlich); the Department of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany (Brosch, Stein, Meller, Ringwald, Schmitt, Steinsträter, Jansen, Krug, Nenadic, Kircher); the Core-Unit Brain Imaging, Faculty of Medicine, University of Marburg, Marburg, Germany (Jansen); the Department of Psychiatry, University of Bonn, Bonn, Germany (Krug); and the University Clinic for Clinical Radiology, University of Münster, Münster, Germany (Kugel, Heindel).

Verena Enneking (V)

From the Department of Psychiatry, University of Münster, Münster, Germany (Förster, Danzer, Redlich, Opel, Grotegerd, Leehr, Dohm, Enneking, Meinert, Goltermann, Lemke, Waltemate, Thiel, Behnert, Hahn, Repple, Dannlowski); the Clinical Psychology and Behavioral Neuroscience, Faculty of Psychology, TU Dresden, Dresden, Germany (Förster); the Department of Clinical Psychology, University of Halle, Halle, Germany (Redlich); the Department of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany (Brosch, Stein, Meller, Ringwald, Schmitt, Steinsträter, Jansen, Krug, Nenadic, Kircher); the Core-Unit Brain Imaging, Faculty of Medicine, University of Marburg, Marburg, Germany (Jansen); the Department of Psychiatry, University of Bonn, Bonn, Germany (Krug); and the University Clinic for Clinical Radiology, University of Münster, Münster, Germany (Kugel, Heindel).

Susanne Meinert (S)

From the Department of Psychiatry, University of Münster, Münster, Germany (Förster, Danzer, Redlich, Opel, Grotegerd, Leehr, Dohm, Enneking, Meinert, Goltermann, Lemke, Waltemate, Thiel, Behnert, Hahn, Repple, Dannlowski); the Clinical Psychology and Behavioral Neuroscience, Faculty of Psychology, TU Dresden, Dresden, Germany (Förster); the Department of Clinical Psychology, University of Halle, Halle, Germany (Redlich); the Department of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany (Brosch, Stein, Meller, Ringwald, Schmitt, Steinsträter, Jansen, Krug, Nenadic, Kircher); the Core-Unit Brain Imaging, Faculty of Medicine, University of Marburg, Marburg, Germany (Jansen); the Department of Psychiatry, University of Bonn, Bonn, Germany (Krug); and the University Clinic for Clinical Radiology, University of Münster, Münster, Germany (Kugel, Heindel).

Janik Goltermann (J)

From the Department of Psychiatry, University of Münster, Münster, Germany (Förster, Danzer, Redlich, Opel, Grotegerd, Leehr, Dohm, Enneking, Meinert, Goltermann, Lemke, Waltemate, Thiel, Behnert, Hahn, Repple, Dannlowski); the Clinical Psychology and Behavioral Neuroscience, Faculty of Psychology, TU Dresden, Dresden, Germany (Förster); the Department of Clinical Psychology, University of Halle, Halle, Germany (Redlich); the Department of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany (Brosch, Stein, Meller, Ringwald, Schmitt, Steinsträter, Jansen, Krug, Nenadic, Kircher); the Core-Unit Brain Imaging, Faculty of Medicine, University of Marburg, Marburg, Germany (Jansen); the Department of Psychiatry, University of Bonn, Bonn, Germany (Krug); and the University Clinic for Clinical Radiology, University of Münster, Münster, Germany (Kugel, Heindel).

Hannah Lemke (H)

From the Department of Psychiatry, University of Münster, Münster, Germany (Förster, Danzer, Redlich, Opel, Grotegerd, Leehr, Dohm, Enneking, Meinert, Goltermann, Lemke, Waltemate, Thiel, Behnert, Hahn, Repple, Dannlowski); the Clinical Psychology and Behavioral Neuroscience, Faculty of Psychology, TU Dresden, Dresden, Germany (Förster); the Department of Clinical Psychology, University of Halle, Halle, Germany (Redlich); the Department of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany (Brosch, Stein, Meller, Ringwald, Schmitt, Steinsträter, Jansen, Krug, Nenadic, Kircher); the Core-Unit Brain Imaging, Faculty of Medicine, University of Marburg, Marburg, Germany (Jansen); the Department of Psychiatry, University of Bonn, Bonn, Germany (Krug); and the University Clinic for Clinical Radiology, University of Münster, Münster, Germany (Kugel, Heindel).

Lena Waltemate (L)

From the Department of Psychiatry, University of Münster, Münster, Germany (Förster, Danzer, Redlich, Opel, Grotegerd, Leehr, Dohm, Enneking, Meinert, Goltermann, Lemke, Waltemate, Thiel, Behnert, Hahn, Repple, Dannlowski); the Clinical Psychology and Behavioral Neuroscience, Faculty of Psychology, TU Dresden, Dresden, Germany (Förster); the Department of Clinical Psychology, University of Halle, Halle, Germany (Redlich); the Department of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany (Brosch, Stein, Meller, Ringwald, Schmitt, Steinsträter, Jansen, Krug, Nenadic, Kircher); the Core-Unit Brain Imaging, Faculty of Medicine, University of Marburg, Marburg, Germany (Jansen); the Department of Psychiatry, University of Bonn, Bonn, Germany (Krug); and the University Clinic for Clinical Radiology, University of Münster, Münster, Germany (Kugel, Heindel).

Katharina Thiel (K)

From the Department of Psychiatry, University of Münster, Münster, Germany (Förster, Danzer, Redlich, Opel, Grotegerd, Leehr, Dohm, Enneking, Meinert, Goltermann, Lemke, Waltemate, Thiel, Behnert, Hahn, Repple, Dannlowski); the Clinical Psychology and Behavioral Neuroscience, Faculty of Psychology, TU Dresden, Dresden, Germany (Förster); the Department of Clinical Psychology, University of Halle, Halle, Germany (Redlich); the Department of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany (Brosch, Stein, Meller, Ringwald, Schmitt, Steinsträter, Jansen, Krug, Nenadic, Kircher); the Core-Unit Brain Imaging, Faculty of Medicine, University of Marburg, Marburg, Germany (Jansen); the Department of Psychiatry, University of Bonn, Bonn, Germany (Krug); and the University Clinic for Clinical Radiology, University of Münster, Münster, Germany (Kugel, Heindel).

Katja Behnert (K)

From the Department of Psychiatry, University of Münster, Münster, Germany (Förster, Danzer, Redlich, Opel, Grotegerd, Leehr, Dohm, Enneking, Meinert, Goltermann, Lemke, Waltemate, Thiel, Behnert, Hahn, Repple, Dannlowski); the Clinical Psychology and Behavioral Neuroscience, Faculty of Psychology, TU Dresden, Dresden, Germany (Förster); the Department of Clinical Psychology, University of Halle, Halle, Germany (Redlich); the Department of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany (Brosch, Stein, Meller, Ringwald, Schmitt, Steinsträter, Jansen, Krug, Nenadic, Kircher); the Core-Unit Brain Imaging, Faculty of Medicine, University of Marburg, Marburg, Germany (Jansen); the Department of Psychiatry, University of Bonn, Bonn, Germany (Krug); and the University Clinic for Clinical Radiology, University of Münster, Münster, Germany (Kugel, Heindel).

Katharina Brosch (K)

From the Department of Psychiatry, University of Münster, Münster, Germany (Förster, Danzer, Redlich, Opel, Grotegerd, Leehr, Dohm, Enneking, Meinert, Goltermann, Lemke, Waltemate, Thiel, Behnert, Hahn, Repple, Dannlowski); the Clinical Psychology and Behavioral Neuroscience, Faculty of Psychology, TU Dresden, Dresden, Germany (Förster); the Department of Clinical Psychology, University of Halle, Halle, Germany (Redlich); the Department of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany (Brosch, Stein, Meller, Ringwald, Schmitt, Steinsträter, Jansen, Krug, Nenadic, Kircher); the Core-Unit Brain Imaging, Faculty of Medicine, University of Marburg, Marburg, Germany (Jansen); the Department of Psychiatry, University of Bonn, Bonn, Germany (Krug); and the University Clinic for Clinical Radiology, University of Münster, Münster, Germany (Kugel, Heindel).

Frederike Stein (F)

From the Department of Psychiatry, University of Münster, Münster, Germany (Förster, Danzer, Redlich, Opel, Grotegerd, Leehr, Dohm, Enneking, Meinert, Goltermann, Lemke, Waltemate, Thiel, Behnert, Hahn, Repple, Dannlowski); the Clinical Psychology and Behavioral Neuroscience, Faculty of Psychology, TU Dresden, Dresden, Germany (Förster); the Department of Clinical Psychology, University of Halle, Halle, Germany (Redlich); the Department of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany (Brosch, Stein, Meller, Ringwald, Schmitt, Steinsträter, Jansen, Krug, Nenadic, Kircher); the Core-Unit Brain Imaging, Faculty of Medicine, University of Marburg, Marburg, Germany (Jansen); the Department of Psychiatry, University of Bonn, Bonn, Germany (Krug); and the University Clinic for Clinical Radiology, University of Münster, Münster, Germany (Kugel, Heindel).

Tina Meller (T)

From the Department of Psychiatry, University of Münster, Münster, Germany (Förster, Danzer, Redlich, Opel, Grotegerd, Leehr, Dohm, Enneking, Meinert, Goltermann, Lemke, Waltemate, Thiel, Behnert, Hahn, Repple, Dannlowski); the Clinical Psychology and Behavioral Neuroscience, Faculty of Psychology, TU Dresden, Dresden, Germany (Förster); the Department of Clinical Psychology, University of Halle, Halle, Germany (Redlich); the Department of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany (Brosch, Stein, Meller, Ringwald, Schmitt, Steinsträter, Jansen, Krug, Nenadic, Kircher); the Core-Unit Brain Imaging, Faculty of Medicine, University of Marburg, Marburg, Germany (Jansen); the Department of Psychiatry, University of Bonn, Bonn, Germany (Krug); and the University Clinic for Clinical Radiology, University of Münster, Münster, Germany (Kugel, Heindel).

Kai Ringwald (K)

From the Department of Psychiatry, University of Münster, Münster, Germany (Förster, Danzer, Redlich, Opel, Grotegerd, Leehr, Dohm, Enneking, Meinert, Goltermann, Lemke, Waltemate, Thiel, Behnert, Hahn, Repple, Dannlowski); the Clinical Psychology and Behavioral Neuroscience, Faculty of Psychology, TU Dresden, Dresden, Germany (Förster); the Department of Clinical Psychology, University of Halle, Halle, Germany (Redlich); the Department of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany (Brosch, Stein, Meller, Ringwald, Schmitt, Steinsträter, Jansen, Krug, Nenadic, Kircher); the Core-Unit Brain Imaging, Faculty of Medicine, University of Marburg, Marburg, Germany (Jansen); the Department of Psychiatry, University of Bonn, Bonn, Germany (Krug); and the University Clinic for Clinical Radiology, University of Münster, Münster, Germany (Kugel, Heindel).

Simon Schmitt (S)

From the Department of Psychiatry, University of Münster, Münster, Germany (Förster, Danzer, Redlich, Opel, Grotegerd, Leehr, Dohm, Enneking, Meinert, Goltermann, Lemke, Waltemate, Thiel, Behnert, Hahn, Repple, Dannlowski); the Clinical Psychology and Behavioral Neuroscience, Faculty of Psychology, TU Dresden, Dresden, Germany (Förster); the Department of Clinical Psychology, University of Halle, Halle, Germany (Redlich); the Department of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany (Brosch, Stein, Meller, Ringwald, Schmitt, Steinsträter, Jansen, Krug, Nenadic, Kircher); the Core-Unit Brain Imaging, Faculty of Medicine, University of Marburg, Marburg, Germany (Jansen); the Department of Psychiatry, University of Bonn, Bonn, Germany (Krug); and the University Clinic for Clinical Radiology, University of Münster, Münster, Germany (Kugel, Heindel).

Olaf Steinsträter (O)

From the Department of Psychiatry, University of Münster, Münster, Germany (Förster, Danzer, Redlich, Opel, Grotegerd, Leehr, Dohm, Enneking, Meinert, Goltermann, Lemke, Waltemate, Thiel, Behnert, Hahn, Repple, Dannlowski); the Clinical Psychology and Behavioral Neuroscience, Faculty of Psychology, TU Dresden, Dresden, Germany (Förster); the Department of Clinical Psychology, University of Halle, Halle, Germany (Redlich); the Department of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany (Brosch, Stein, Meller, Ringwald, Schmitt, Steinsträter, Jansen, Krug, Nenadic, Kircher); the Core-Unit Brain Imaging, Faculty of Medicine, University of Marburg, Marburg, Germany (Jansen); the Department of Psychiatry, University of Bonn, Bonn, Germany (Krug); and the University Clinic for Clinical Radiology, University of Münster, Münster, Germany (Kugel, Heindel).

Andreas Jansen (A)

From the Department of Psychiatry, University of Münster, Münster, Germany (Förster, Danzer, Redlich, Opel, Grotegerd, Leehr, Dohm, Enneking, Meinert, Goltermann, Lemke, Waltemate, Thiel, Behnert, Hahn, Repple, Dannlowski); the Clinical Psychology and Behavioral Neuroscience, Faculty of Psychology, TU Dresden, Dresden, Germany (Förster); the Department of Clinical Psychology, University of Halle, Halle, Germany (Redlich); the Department of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany (Brosch, Stein, Meller, Ringwald, Schmitt, Steinsträter, Jansen, Krug, Nenadic, Kircher); the Core-Unit Brain Imaging, Faculty of Medicine, University of Marburg, Marburg, Germany (Jansen); the Department of Psychiatry, University of Bonn, Bonn, Germany (Krug); and the University Clinic for Clinical Radiology, University of Münster, Münster, Germany (Kugel, Heindel).

Axel Krug (A)

From the Department of Psychiatry, University of Münster, Münster, Germany (Förster, Danzer, Redlich, Opel, Grotegerd, Leehr, Dohm, Enneking, Meinert, Goltermann, Lemke, Waltemate, Thiel, Behnert, Hahn, Repple, Dannlowski); the Clinical Psychology and Behavioral Neuroscience, Faculty of Psychology, TU Dresden, Dresden, Germany (Förster); the Department of Clinical Psychology, University of Halle, Halle, Germany (Redlich); the Department of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany (Brosch, Stein, Meller, Ringwald, Schmitt, Steinsträter, Jansen, Krug, Nenadic, Kircher); the Core-Unit Brain Imaging, Faculty of Medicine, University of Marburg, Marburg, Germany (Jansen); the Department of Psychiatry, University of Bonn, Bonn, Germany (Krug); and the University Clinic for Clinical Radiology, University of Münster, Münster, Germany (Kugel, Heindel).

Igor Nenadic (I)

From the Department of Psychiatry, University of Münster, Münster, Germany (Förster, Danzer, Redlich, Opel, Grotegerd, Leehr, Dohm, Enneking, Meinert, Goltermann, Lemke, Waltemate, Thiel, Behnert, Hahn, Repple, Dannlowski); the Clinical Psychology and Behavioral Neuroscience, Faculty of Psychology, TU Dresden, Dresden, Germany (Förster); the Department of Clinical Psychology, University of Halle, Halle, Germany (Redlich); the Department of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany (Brosch, Stein, Meller, Ringwald, Schmitt, Steinsträter, Jansen, Krug, Nenadic, Kircher); the Core-Unit Brain Imaging, Faculty of Medicine, University of Marburg, Marburg, Germany (Jansen); the Department of Psychiatry, University of Bonn, Bonn, Germany (Krug); and the University Clinic for Clinical Radiology, University of Münster, Münster, Germany (Kugel, Heindel).

Tilo Kircher (T)

From the Department of Psychiatry, University of Münster, Münster, Germany (Förster, Danzer, Redlich, Opel, Grotegerd, Leehr, Dohm, Enneking, Meinert, Goltermann, Lemke, Waltemate, Thiel, Behnert, Hahn, Repple, Dannlowski); the Clinical Psychology and Behavioral Neuroscience, Faculty of Psychology, TU Dresden, Dresden, Germany (Förster); the Department of Clinical Psychology, University of Halle, Halle, Germany (Redlich); the Department of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany (Brosch, Stein, Meller, Ringwald, Schmitt, Steinsträter, Jansen, Krug, Nenadic, Kircher); the Core-Unit Brain Imaging, Faculty of Medicine, University of Marburg, Marburg, Germany (Jansen); the Department of Psychiatry, University of Bonn, Bonn, Germany (Krug); and the University Clinic for Clinical Radiology, University of Münster, Münster, Germany (Kugel, Heindel).

Tim Hahn (T)

From the Department of Psychiatry, University of Münster, Münster, Germany (Förster, Danzer, Redlich, Opel, Grotegerd, Leehr, Dohm, Enneking, Meinert, Goltermann, Lemke, Waltemate, Thiel, Behnert, Hahn, Repple, Dannlowski); the Clinical Psychology and Behavioral Neuroscience, Faculty of Psychology, TU Dresden, Dresden, Germany (Förster); the Department of Clinical Psychology, University of Halle, Halle, Germany (Redlich); the Department of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany (Brosch, Stein, Meller, Ringwald, Schmitt, Steinsträter, Jansen, Krug, Nenadic, Kircher); the Core-Unit Brain Imaging, Faculty of Medicine, University of Marburg, Marburg, Germany (Jansen); the Department of Psychiatry, University of Bonn, Bonn, Germany (Krug); and the University Clinic for Clinical Radiology, University of Münster, Münster, Germany (Kugel, Heindel).

Harald Kugel (H)

From the Department of Psychiatry, University of Münster, Münster, Germany (Förster, Danzer, Redlich, Opel, Grotegerd, Leehr, Dohm, Enneking, Meinert, Goltermann, Lemke, Waltemate, Thiel, Behnert, Hahn, Repple, Dannlowski); the Clinical Psychology and Behavioral Neuroscience, Faculty of Psychology, TU Dresden, Dresden, Germany (Förster); the Department of Clinical Psychology, University of Halle, Halle, Germany (Redlich); the Department of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany (Brosch, Stein, Meller, Ringwald, Schmitt, Steinsträter, Jansen, Krug, Nenadic, Kircher); the Core-Unit Brain Imaging, Faculty of Medicine, University of Marburg, Marburg, Germany (Jansen); the Department of Psychiatry, University of Bonn, Bonn, Germany (Krug); and the University Clinic for Clinical Radiology, University of Münster, Münster, Germany (Kugel, Heindel).

Walter Heindel (W)

From the Department of Psychiatry, University of Münster, Münster, Germany (Förster, Danzer, Redlich, Opel, Grotegerd, Leehr, Dohm, Enneking, Meinert, Goltermann, Lemke, Waltemate, Thiel, Behnert, Hahn, Repple, Dannlowski); the Clinical Psychology and Behavioral Neuroscience, Faculty of Psychology, TU Dresden, Dresden, Germany (Förster); the Department of Clinical Psychology, University of Halle, Halle, Germany (Redlich); the Department of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany (Brosch, Stein, Meller, Ringwald, Schmitt, Steinsträter, Jansen, Krug, Nenadic, Kircher); the Core-Unit Brain Imaging, Faculty of Medicine, University of Marburg, Marburg, Germany (Jansen); the Department of Psychiatry, University of Bonn, Bonn, Germany (Krug); and the University Clinic for Clinical Radiology, University of Münster, Münster, Germany (Kugel, Heindel).

Jonathan Repple (J)

From the Department of Psychiatry, University of Münster, Münster, Germany (Förster, Danzer, Redlich, Opel, Grotegerd, Leehr, Dohm, Enneking, Meinert, Goltermann, Lemke, Waltemate, Thiel, Behnert, Hahn, Repple, Dannlowski); the Clinical Psychology and Behavioral Neuroscience, Faculty of Psychology, TU Dresden, Dresden, Germany (Förster); the Department of Clinical Psychology, University of Halle, Halle, Germany (Redlich); the Department of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany (Brosch, Stein, Meller, Ringwald, Schmitt, Steinsträter, Jansen, Krug, Nenadic, Kircher); the Core-Unit Brain Imaging, Faculty of Medicine, University of Marburg, Marburg, Germany (Jansen); the Department of Psychiatry, University of Bonn, Bonn, Germany (Krug); and the University Clinic for Clinical Radiology, University of Münster, Münster, Germany (Kugel, Heindel).

Udo Dannlowski (U)

From the Department of Psychiatry, University of Münster, Münster, Germany (Förster, Danzer, Redlich, Opel, Grotegerd, Leehr, Dohm, Enneking, Meinert, Goltermann, Lemke, Waltemate, Thiel, Behnert, Hahn, Repple, Dannlowski); the Clinical Psychology and Behavioral Neuroscience, Faculty of Psychology, TU Dresden, Dresden, Germany (Förster); the Department of Clinical Psychology, University of Halle, Halle, Germany (Redlich); the Department of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany (Brosch, Stein, Meller, Ringwald, Schmitt, Steinsträter, Jansen, Krug, Nenadic, Kircher); the Core-Unit Brain Imaging, Faculty of Medicine, University of Marburg, Marburg, Germany (Jansen); the Department of Psychiatry, University of Bonn, Bonn, Germany (Krug); and the University Clinic for Clinical Radiology, University of Münster, Münster, Germany (Kugel, Heindel).

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Social support and hippocampal volume are...
questionsmedicales.fr › Personnes › Tranches d'âge › Enfant › Social support and hippocampal volume are...
questionsmedicales.fr › Sciences sociales › Sociologie › Problèmes sociaux › Violence › Violence domestique › Maltraitance des enfants › Social support and hippocampal volume are...
questionsmedicales.fr › Système nerveux › Système nerveux central › Encéphale › Prosencéphale › Télencéphale › Cerveau › Cortex cérébral › Hippocampe › Social support and hippocampal volume are...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Social support and hippocampal volume are...
questionsmedicales.fr › Phénomènes physiologiques › Croissance et développement › Croissance › Taille d'organe › Social support and hippocampal volume are...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Statistiques comme sujet › Probabilité › Risque › Facteurs de protection › Social support and hippocampal volume are...
questionsmedicales.fr › Sciences sociales › Sociologie › Facteurs sociologiques › Environnement social › Soutien social › Social support and hippocampal volume are...