Review of the mechanism underlying mefloquine-induced neurotoxicity.

Antimalarials / toxicity Central Nervous System Humans Mefloquine / toxicity Nervous System / drug effects
Mefloquine Pyk2 calcium homeostasis neurotoxicity oxidative stress

Journal

Critical reviews in toxicology
ISSN: 1547-6898
Titre abrégé: Crit Rev Toxicol
Pays: England
ID NLM: 8914275

Informations de publication

Date de publication:
03 2021
Historique:
pubmed: 28 4 2021
medline: 3 9 2021
entrez: 27 4 2021
Statut: ppublish

Résumé

Mefloquine, a potent blood schizontocide, is effective against drug-resistant

Identifiants

DOI: 10.1080/10408444.2021.1901258 PMID: 33905310
pubmed: 33905310
doi: 10.1080/10408444.2021.1901258
doi:

Substances chimiques

Antimalarials 0
Mefloquine TML814419R

Types de publication

Journal Article Research Support, N.I.H., Extramural Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

209-216

Subventions

Organisme : NIEHS NIH HHS
ID : R01 ES007331
Pays : United States
Organisme : NIEHS NIH HHS
ID : R01 ES010563
Pays : United States

Auteurs

Airton C Martins (AC)

Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY, USA.

Monica M B Paoliello (MMB)

Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY, USA.

Anca O Docea (AO)

Department of Toxicology, University of Medicine and Pharmacy of Craiova, Craiova, Romania.

Abel Santamaria (A)

Laboratorio de Aminoacidos Excitadores, Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez, Mexico City, Mexico.

Alexey A Tinkov (AA)

I.M. Sechenov First, Moscow State Medical University (Sechenov University), Moscow, Russia.
KG Razumovsky Moscow State University of Technologies and Management, Moscow, Russia.

Anatoly V Skalny (AV)

I.M. Sechenov First, Moscow State Medical University (Sechenov University), Moscow, Russia.
KG Razumovsky Moscow State University of Technologies and Management, Moscow, Russia.

Michael Aschner (M)

Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY, USA.
I.M. Sechenov First, Moscow State Medical University (Sechenov University), Moscow, Russia.
ORCID: 0000-0002-2619-1656

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antiparasitaires › Antiprotozoaires › Antipaludiques › Review of the mechanism underlying...
questionsmedicales.fr › Système nerveux › Système nerveux central › Review of the mechanism underlying...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Review of the mechanism underlying...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Quinoléines › Méfloquine › Review of the mechanism underlying...
questionsmedicales.fr › Système nerveux › Review of the mechanism underlying...