Thermosensitive Biodegradable Copper Sulfide Nanoparticles for Real-Time Multispectral Optoacoustic Tomography.
biodegradable
copper sulfide
multispectral optoacoustic tomography
nanoparticles
thermosensitive
Journal
ACS applied bio materials
ISSN: 2576-6422
Titre abrégé: ACS Appl Bio Mater
Pays: United States
ID NLM: 101729147
Informations de publication
Date de publication:
19 Aug 2019
19 Aug 2019
Historique:
entrez:
28
4
2021
pubmed:
19
8
2019
medline:
19
8
2019
Statut:
ppublish
Résumé
Although multifunctional inorganic nanoparticles have been extensively explored for effective cancer diagnosis and therapy, their clinical translation has been greatly impeded because of significant uptake in the reticuloendothelial system and concerns about potential toxicity. In this study, we uncovered the thermosensitive biodegradability of CuS nanoparticles, which have classically been considered as stable in bulk state. Polyethylene glycol (PEG)-coated CuS nanoparticles (CuS-PEG) were well preserved at 4 ºC but were rapidly degraded at 37 ºC within 1 week in both
Identifiants
pubmed: 33907729
doi: 10.1021/acsabm.9b00133
pmc: PMC8075272
mid: NIHMS1065888
doi:
Types de publication
Journal Article
Langues
eng
Pagination
3203-3211Subventions
Organisme : NCI NIH HHS
ID : P30 CA016672
Pays : United States
Organisme : NIH HHS
ID : S10 OD019946
Pays : United States
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