An improved method to estimate absolute blood volume based on dialysate dilution.

absolute blood volume blood volume monitoring chronic hemodialysis dialysate dilution volume management

Journal

Artificial organs
ISSN: 1525-1594
Titre abrégé: Artif Organs
Pays: United States
ID NLM: 7802778

Informations de publication

Date de publication:
Sep 2021
Historique:
revised: 09 02 2021
received: 06 01 2021
accepted: 12 04 2021
pubmed: 29 4 2021
medline: 5 1 2022
entrez: 28 4 2021
Statut: ppublish

Résumé

Online hemodiafiltration machines equipped with a blood volume monitor and the possibility to rapidly infuse exact amounts of ultrapure dialysate into the extracorporeal circulation can be used to determine absolute blood volume in clinical practice. The aim of the present study was to evaluate the reproducibility of such measurements. Intra-individual reproducibility was evaluated in four measurements taken in hourly intervals within the same dialysis treatment. Ten patients were studied. Absolute blood volumes measured at the beginning and after 1 hour of dialysis were significantly different (80.6 ± 14.5 and 63.9 ± 14.3 mL/kg, P < .001) and highly reproducible between the last three measurements (63.9 ± 14.3, 61.4 ± 13.8, and 60.9 ± 13.9 mL/kg, P = n.s.). Measurement of absolute blood volume after 1 hour of treatment is more precise than earlier measurements and might be better suited for guidance of ultrafiltration.

Identifiants

pubmed: 33908065
doi: 10.1111/aor.13970
doi:

Substances chimiques

Dialysis Solutions 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

E359-E363

Informations de copyright

© 2021 International Center for Artificial Organs and Transplantation and Wiley Periodicals, Inc.

Références

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Auteurs

Susanne Kron (S)

Department of Nephrology and Internal Intensive Care Medicine, Charité-Universitätsmedizin Berlin, Berlin, Germany.

Daniel Schneditz (D)

Division of Physiology, Otto Loewi Research Center, Medical University of Graz, Graz, Austria.

David F Keane (DF)

Department of Renal Medicine, Leeds Teaching Hospitals, Leeds, UK.

Til Leimbach (T)

KfH Kidney Center Berlin-Köpenick, Berlin, Germany.

Joachim Kron (J)

KfH Kidney Center Berlin-Köpenick, Berlin, Germany.

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