Human Health Risk Assessments and Characterization of Nanomaterials: Are We Ready for the Next (Active) Generations?

active nanostructures nanotechnology next generations risk assessments

Journal

Annals of work exposures and health
ISSN: 2398-7316
Titre abrégé: Ann Work Expo Health
Pays: England
ID NLM: 101698454

Informations de publication

Date de publication:
05 08 2021
Historique:
received: 30 10 2020
revised: 10 12 2020
accepted: 14 01 2021
pubmed: 29 4 2021
medline: 14 8 2021
entrez: 28 4 2021
Statut: ppublish

Résumé

Driven by the concept of the 'four generations of nanomaterials', the current state of the knowledge on risk assessment of future generation is explored for active nanomaterials. Through case studies, we identify challenges and evaluate the preparedness of characterization methods, available risk assessment modeling tools, and analytical instrumentation for such future generation active nanomaterials with dynamic hybrid structures of biotic-abiotic and organic-inorganic combinations. Currently available risk assessment tools and analytical instrumentation were found to be lacking the risk preparedness and characterization readiness for active nanomaterials, respectively. Potential future developments in risk assessment modeling tools and analytical techniques can be based upon this work which shall ensure long-term safety of the next generation of nanomaterials.

Identifiants

pubmed: 33909008
pii: 6257015
doi: 10.1093/annweh/wxab005
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

748-759

Informations de copyright

© The Author(s) 2021. Published by Oxford University Press on behalf of the British Occupational Hygiene Society.

Auteurs

Petra Krystek (P)

Environmental Modelling Sensing & Analysis (EMSA), Netherlands Organisation for Applied Scientific Research (TNO), Princetonlaan 6, 3584 CB Utrecht, The Netherlands.

Neeraj Shandilya (N)

Risk Analysis for Products in Development (RAPID), Netherlands Organisation for Applied Scientific Research (TNO), Princetonlaan 6, 3584 CB Utrecht, The Netherlands.

Wouter Fransman (W)

Risk Analysis for Products in Development (RAPID), Netherlands Organisation for Applied Scientific Research (TNO), Princetonlaan 6, 3584 CB Utrecht, The Netherlands.

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Classifications MeSH