Evaluation of 3D-printed molds for fabrication of non-planar microchannels.


Journal

Biomicrofluidics
ISSN: 1932-1058
Titre abrégé: Biomicrofluidics
Pays: United States
ID NLM: 101293825

Informations de publication

Date de publication:
Mar 2021
Historique:
received: 14 02 2021
accepted: 26 03 2021
entrez: 29 4 2021
pubmed: 30 4 2021
medline: 30 4 2021
Statut: epublish

Résumé

Replica obtained from micromolds patterned by simple photolithography has features with uniform heights, and attainable microchannels are thus quasi-two-dimensional. Recent progress in three-dimensional (3D) printing has enabled facile desktop fabrication of molds to replicate microchannels with varying heights. We investigated the replica obtained from four common techniques of 3D printing-fused deposition modeling, selective laser sintering, photo-polymer inkjet printing (PJ), and stereolithography (SL)-for the suitability to form microchannels in terms of the surface roughness inherent to the mechanism of 3D printing. There have been limited quantitative studies that focused on the surface roughness of a 3D-printed mold with different methods of 3D printing. We discussed that the surface roughness of the molds affected (1) transparency of the replica and (2) delamination pressure of poly(dimethylsiloxane) replica bonded to flat glass substrates. Thereafter, we quantified the accuracy of replication from 3D-printed molds by comparing the dimensions of the replicated parts to the designed dimensions and tested the ability to fabricate closely spaced microchannels. This study suggested that molds printed by PJ and SL printers were suitable for replica molding to fabricate microchannels with varying heights. The insight from this study shall be useful to fabricate 3D microchannels with controlled 3D patterns of flows guided by the geometry of the microchannels.

Identifiants

pubmed: 33912266
doi: 10.1063/5.0047497
pii: 5.0047497
pmc: PMC8057840
doi:

Types de publication

Journal Article

Langues

eng

Pagination

024111

Informations de copyright

© 2021 Author(s).

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Auteurs

Patrick S Doyle (PS)

Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave., Cambridge, Massachusetts 02139, USA.

Classifications MeSH