Evaluation of Anti-plaque and Anti-inflammatory Effects of Oral Curcumin Gel as Adjunct to Scaling and Root Planing: A Clinical Study.
Curcumin gel
gingivitis
scaling and root planing
Journal
International journal of applied & basic medical research
ISSN: 2229-516X
Titre abrégé: Int J Appl Basic Med Res
Pays: India
ID NLM: 101579831
Informations de publication
Date de publication:
Historique:
received:
22
11
2019
revised:
02
12
2020
accepted:
24
02
2021
entrez:
29
4
2021
pubmed:
30
4
2021
medline:
30
4
2021
Statut:
ppublish
Résumé
The adverse effects associated with traditional adjunctive chemical agents in the management of gingivitis has stimulated research into search for alternate molecules including herbal products. Aims-To compare the effects of oral curcumin gel as an adjunct to scaling and root planing (SRP) with the effects achieved by SRP alone by assessing their effects on plaque, gingival inflammation and gingival bleeding. Sixty patients in the age group of 20-60 years were recruited employing inclusion and exclusion criteria. Study population was randomly divided into two groups. Group A-test group was instructed to use twice daily the experimental curcumin gel after initial SRP. Group B-control group received only SRP. Parameters recorded were plaque index (PI), gingival index (GI) and sulcus bleeding index (SBI) on day 0 (baseline), days 7, 14, and 21 along with subjective assessment of any reported untoward side effect. Data was analyzed statistically. The PI, GI and SBI decreased in both the test group and control group from day 0 to day 21 consecutively. Intergroup comparison shows that all the parameters were statistically significant in Group A ( Curcumin gel has significant antiplaque and anti-inflammatory effect in the treatment of gingivitis and can be effectively employed as an adjunct to SRP.
Identifiants
pubmed: 33912428
doi: 10.4103/ijabmr.IJABMR_391_19
pii: IJABMR-11-90
pmc: PMC8061619
doi:
Types de publication
Journal Article
Langues
eng
Pagination
90-94Informations de copyright
Copyright: © 2021 International Journal of Applied and Basic Medical Research.
Déclaration de conflit d'intérêts
There are no conflicts of interest.
Références
J Prev Dent. 1977 Jul-Aug;4(4):6-17
pubmed: 275483
Indian J Med Res. 1980 Apr;71:632-4
pubmed: 7390600
J Indian Soc Periodontol. 2014 Sep;18(5):575-80
pubmed: 25425818
J Pharm Bioallied Sci. 2015 Aug;7(Suppl 2):S554-8
pubmed: 26538916
Curr Pharm Des. 2013;19(11):2032-46
pubmed: 23116311
J Periodontol. 2005 Aug;76(8):1406-19
pubmed: 16101377
Acta Odontol Scand. 1964 Feb;22:121-35
pubmed: 14158464
Int J Pharm Investig. 2017 Oct-Dec;7(4):188-192
pubmed: 29692978
Aust Dent J. 2009 Sep;54 Suppl 1:S96-101
pubmed: 19737272
J Indian Soc Periodontol. 2017 Mar-Apr;21(2):132-137
pubmed: 29398858
Adv Med Sci. 2011;56(2):123-31
pubmed: 22112427
J Altern Complement Med. 2004 Dec;10(6):1015-8
pubmed: 15673996
J Indian Soc Periodontol. 2017 Nov-Dec;21(6):478-483
pubmed: 29551867
J Periodontol. 2016 Jan;87(1):83-90
pubmed: 26447754
J Altern Complement Med. 2003 Feb;9(1):161-8
pubmed: 12676044
Indian J Med Res. 1971 Aug;59(8):1289-95
pubmed: 5132235
J Clin Diagn Res. 2014 Dec;8(12):ZC08-10
pubmed: 25654020
Acta Odontol Scand. 1963 Dec;21:533-51
pubmed: 14121956
Indian J Dent Res. 2015 Jan-Feb;26(1):53-6
pubmed: 25961616
Oral Health Prev Dent. 2013;11(1):81-6
pubmed: 23507685
Cell Biol Int. 2013 May;37(5):443-8
pubmed: 23494805