Atypical Presentation of Granular Cell Tumor Involving Tongue: A Rare Case Report.
Exophytic
granular cell tumor
immunohistochemistry
tongue
Journal
International journal of applied & basic medical research
ISSN: 2229-516X
Titre abrégé: Int J Appl Basic Med Res
Pays: India
ID NLM: 101579831
Informations de publication
Date de publication:
Historique:
received:
30
12
2019
revised:
02
12
2020
accepted:
31
01
2021
entrez:
29
4
2021
pubmed:
30
4
2021
medline:
30
4
2021
Statut:
ppublish
Résumé
Granular cell tumor (GCT) is a rare benign tumor chiefly affecting the orofacial region, especially tongue. The origin of this neoplasia, after remaining a controversy for years, was finally identified to be from Schwann cell or neuroendocrine cell. They usually present as asymptomatic, firm, sessile, submucosal, solitary, or multiple nodule/papule like lesions. Histopathologically, the presence of sheets, cords or nests of large cells having abundant, eosinophilic granular cytoplasm, and pseudoepitheliomatous hyperplasia are the characteristic features of this neoplasm. Immunohistochemical stains such as S100, Cluster of differentiation 68, neuron-specific enolase, and laminin also aid in the proper diagnosis of granular cells. We hereby present a case of GCT in a 50-year-old male, which had a unique exophytic appearance, probably being only the second to be reported till date.
Identifiants
pubmed: 33912433
doi: 10.4103/ijabmr.IJABMR_438_19
pii: IJABMR-11-111
pmc: PMC8061612
doi:
Types de publication
Case Reports
Langues
eng
Pagination
111-113Informations de copyright
Copyright: © 2021 International Journal of Applied and Basic Medical Research.
Déclaration de conflit d'intérêts
There are no conflicts of interest.
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