The cervical spine demonstrates less postoperative bone loss than the lumbar spine.
anterior cervical discectomy and fusion
bone mineral density
osteoporosis
postoperative change
quantitative computed tomography
Journal
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
ISSN: 1554-527X
Titre abrégé: J Orthop Res
Pays: United States
ID NLM: 8404726
Informations de publication
Date de publication:
Mar 2022
Mar 2022
Historique:
revised:
21
04
2021
received:
01
12
2020
accepted:
26
04
2021
pubmed:
30
4
2021
medline:
19
4
2022
entrez:
29
4
2021
Statut:
ppublish
Résumé
The objective of this study is to determine the bone mineral density (BMD) changes in adjacent vertebra following anterior cervical discectomy and fusion (ACDF). Consecutive patients undergoing ACDF with available preoperative and postoperative computed tomography (CT) imaging were included. Quantitative CT measurements of screw-free cervical and first thoracic vertebra were performed. Comparisons between pre- and postoperative BMD in the vertebrae one or two levels above the upper instrumented vertebra (UIV + 1, UIV + 2) and one level below the lowest instrumented vertebra (LIV + 1) were assessed. Seventy-two patients (men, 66.7%) met the inclusion criteria. The patient population was 91.7% Caucasian with a mean age of 55.0 years. The mean interval (±SD) between surgery and secondary CT was 157 ± 23 days. Preoperative BMD (±SD) in UIV + 1 was 300.6 ± 66.2 mg/cm
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
654-660Informations de copyright
© 2021 Orthopaedic Research Society. Published by Wiley Periodicals LLC.
Références
Guzman JZ, Feldman ZM, McAnany S, Hecht AC, Qureshi SA, Cho SK. Osteoporosis in cervical spine surgery. Spine (Phila. Pa. 1976). 2016;41(8):662-668.
Lipscomb HJ, Grubb SA, Talmage RV. Spinal bone density following spinal fusion. Spine (Phila. Pa. 1976). 1989;14(4):477-479.
Mitchell Bogdanffy G, Ohnmeiss DD, Guyer RD. Early changes in bone mineral density above a combined anteroposterior L4- S1 lumbar spinal fusion: a clinical investigation. Spine (Phila. Pa. 1976). 1995;20(15):1674-1678.
Myers MA, Casciani T, Whitbeck MG, Puzas JE. Vertebral body osteopenia associated with posterolateral spine fusion in humans. Spine (Phila. Pa. 1976). 1996;21(20):2368-2371.
Erdogan B, Bagis T, Sen O, et al. Effects of lumbar disc surgery on bone mineral density in women with lumbar disc disease. Adv Ther. 2003;20(2):114-120.
Balci A, Kalemci O, Kaya FG, Akyoldas G, Yucesoy K, Ozaksoy D. Early and long-term changes in adjacent vertebral body bone mineral density determined by quantitative computed tomography after posterolateral fusion with transpedicular screw fixation. Clin Neurol Neurosurg. 2016;145(2016):84-88.
Demir Ö, Öksüz E, Deniz FE, Demir O. Assessing the effects of lumbar posterior stabilization and fusion to vertebral bone density in stabilized and adjacent segments by using Hounsfield unit. J Spine Surg. 2017;3(4):548-553.
Korovessis P, Konstantinou D, Piperos G, Partheni M, Tzorztidis F, Papadakis N. Spinal bone mineral density changes following halo vest immobilization for cervical trauma. Eur Spine J. 1994;3(4):206-208.
Takahashi J, Ebara S, Kamimura M, et al. Pro-inflammatory and anti-inflammatory cytokine increases after spinal instrumentation surgery. J Spinal Disord Tech. 2002;15(4):294-300.
Dubrovsky AM, Lim MJ, Lane NE. Osteoporosis in rheumatic diseases: anti-rheumatic drugs and the skeleton. Calcif Tissue Int. 2018;102(5):607-618.
Haugeberg G, Uhlig T, Falch JA, Halse JI, Kvien TK. Bone mineral density and frequency of osteoporosis in female patients with rheumatoid arthritis: Results from 394 patients in the Oslo County rheumatoid arthritis register. Arthritis Rheum. 2000;43(3):522-530.
Guthrie JR, Ebeling PR, Hopper JL, et al. A prospective study of bone loss in menopausal Australian-born women. Osteoporos Int. 1998;8(3):282-290.
Recker RR, Lappe JM, Davies KM, Kimmel DB. Change in bone mass immediately before menopause. J Bone Miner Res. 1992;7(8):857-862.
Oglesby M, Fineberg SJ, Patel Aa, Pelton MA, Singh K. Epidemiological trends in cervical spine surgery for degenerative diseases between 2002 and 2009. Spine (Phila. Pa. 1976). 2013;38(14):1226-1232.
Salzmann SN, Derman PB, Lampe LP, et al. Cervical Spinal Fusion: 16-Year trends in epidemiology, indications, and in-hospital outcomes by surgical approach. World Neurosurg. 2018;113:e280-e295.
Marawar S, Girardi FP, Sama AA, et al. National trends in anterior cervical fusion procedures. Spine (Phila. Pa. 1976). 2010;35(15):1454-1459.
Hitchon PW, Brenton MD, Coppes JK, From AM, Torner JC. Factors affecting the pullout strength of self-drilling and self-tapping anterior cervical screws. Spine (Phila. Pa. 1976). 2003;28(1):9-13.
Ordway NR, Lu YM, Zhang X, Cheng CC, Fang H, Fayyazi AH. Correlation of cervical endplate strength with CT measured subchondral bone density. Eur Spine J. 2007;16(12):2104-2109.
Truumees E, Demetropoulos CK, Yang KH, Herkowitz HN. Failure of human cervical endplates: A cadaveric experimental model. Spine (Phila. Pa. 1976). 2003;28(19):2204-2208.
Brown JK, Timm W, Bodeen G, et al. Asynchronously calibrated quantitative bone densitometry. J Clin Densitom. 2017;20(2):216-225.
Wang L, Su Y, Wang Q, et al. Validation of asynchronous quantitative bone densitometry of the spine: Accuracy, short-term reproducibility, and a comparison with conventional quantitative computed tomography. Sci Rep. 2017;7(1):1-7.
Shepherd JA, Schousboe JT, Broy SB, Engelke K, Leslie WD. Executive summary of the 2015 ISCD position development conference on advanced measures From DXA and QCT: fracture prediction beyond BMD. J Clin Densitom. 2015;18(3):274-286.
Zhang X, Ordway NR, Tan R, Rim BC, Fayyazi AH. Correlation of prodisc-C failure strength with cervical bone mineral content and endplate strength. J Spinal Disord Tech. 2008;21(6):400-405.
Engelke K, Lang T, Khosla S, et al. Clinical Use of Quantitative Computed Tomography (QCT) of the Hip in the Management of Osteoporosis in Adults: The 2015 ISCD Official Positions-Part I. J Clin Densitom. 2015;18(3):338-358.
Schoenau E, Land C, Stabrey A, Remer T, Kroke A. The bone mass concept: problems in short stature. Eur J Endocrinol. 2004;151(Suppl(6)):S87-S91.
Tothill P, Pye DW. Errors due to non-uniform distribution of fat in dual X-ray absorptiometry of the lumbar spine. Br J Radiol. 1992;65(777):807-813.
Smith JA, Vento JA, Spencer RP, Tendler BE. Aortic calcification contributing to bone densitometry measurement. J Clin Densitom. 1999;2(2):181-183.
Rand T, Seidl G, Kainberger F, et al. Impact of spinal degenerative changes on the evaluation of bone mineral density with dual energy X-ray absorptiometry (DXA). Calcif Tissue Int. 1997;60(5):430-433.
Link TM. Osteoporosis imaging: state of the art and advanced imaging. Radiology. 2012;263(1):3-17.
Yoganandan N, Pintar FA, Stemper BD, et al. Trabecular bone density of male human cervical and lumbar vertebrae. Bone. 2006;39(2):336-344.
Guglielmi G, Floriani I, Torri V, et al. Effect of spinal degenerative changes on volumetric bone mineral density of the central skeleton as measured by quantitative computed tomography. Acta Radiol. 2005;46(3):269-275.
Löffler MT, Jacob A, Valentinitsch A, et al. Improved prediction of incident vertebral fractures using opportunistic QCT compared to DXA. Eur Radiol. 2019;29(9):4980-4989.
Eisa F, Museyko O, Hess A, Kalender WA, Engelke K. Comparison of anatomic coordinate systems with rigid multi-resolution 3D registration for the reproducible positioning of analysis volumes of interest in QCT. Phys Med Biol. 2010;55(5):1429-1439.
Salzmann SN, Shirahata T, Yang J, et al. Regional bone mineral density differences measured by quantitative computed tomography: does the standard clinically used L1-L2 average correlate with the entire lumbosacral spine? Spine J. 2019;19(4):695-702.
Yoganandan N, Pintar FA, Stemper BD, et al. Bone mineral density of human female cervical and lumbar spines from quantitative computed tomography. Spine (Phila. Pa. 1976). 2006;31(1):73-76.
Anderst WJ, Thorhauer ED, Lee JY, Donaldson WF, Kang JD. Cervical spine bone mineral density as a function of vertebral level and anatomic location. Spine J. 2011;11(7):659-667.
Koller H, Hempfing A, Ferraris L, Maier O, Hitzl W, Metz-Stavenhagen P. 4- And 5-level anterior fusions of the cervical spine: Review of literature and clinical results. Eur Spine J. 2007;16(12):2055-2071.
Noordhoek I, Koning MT, Jacobs WCH, Vleggeert-Lankamp CLA. Incidence and clinical relevance of cage subsidence in anterior cervical discectomy and fusion: a systematic review. Acta Neurochir (Wien). 2018;160(4):873-880.
Seaman S, Kerezoudis P, Bydon M, Torner JC, Hitchon PW. Titanium vs. polyetheretherketone (PEEK) interbody fusion: Meta-analysis and review of the literature. J Clin Neurosci. 2017;44:23-29.