Effectiveness of collaborative care in reducing suicidal ideation: An individual participant data meta-analysis.


Journal

General hospital psychiatry
ISSN: 1873-7714
Titre abrégé: Gen Hosp Psychiatry
Pays: United States
ID NLM: 7905527

Informations de publication

Date de publication:
Historique:
received: 02 03 2021
revised: 15 04 2021
accepted: 18 04 2021
pubmed: 30 4 2021
medline: 31 12 2021
entrez: 29 4 2021
Statut: ppublish

Résumé

To assess whether CC is more effective at reducing suicidal ideation in people with depression compared with usual care, and whether study and patient factors moderate treatment effects. We searched Medline, Embase, PubMed, PsycINFO, CINAHL, CENTRAL from inception to March 2020 for Randomised Controlled Trials (RCTs) that compared the effectiveness of CC with usual care in depressed adults, and reported changes in suicidal ideation at 4 to 6 months post-randomisation. Mixed-effects models accounted for clustering of participants within trials and heterogeneity across trials. This study is registered with PROSPERO, CRD42020201747. We extracted data from 28 RCTs (11,165 patients) of 83 eligible studies. We observed a small significant clinical improvement of CC on suicidal ideation, compared with usual care (SMD, -0.11 [95%CI, -0.15 to -0.08]; I Primary care based CC with an embedded psychological intervention is the most effective CC framework for reducing suicidal ideation and older patients may benefit the most.

Identifiants

pubmed: 33915444
pii: S0163-8343(21)00054-2
doi: 10.1016/j.genhosppsych.2021.04.004
pii:
doi:

Types de publication

Journal Article Meta-Analysis Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

27-35

Informations de copyright

Copyright © 2021 The Authors. Published by Elsevier Inc. All rights reserved.

Auteurs

Christos Grigoroglou (C)

Division of Population Health, Health Services Research & Primary Care, University of Manchester, Manchester, England. Electronic address: Christos.grigoroglou@manchester.ac.uk.

Christina van der Feltz-Cornelis (C)

Department of Health Sciences, Hull York Medical School, HYMS, University of York, York, England.

Alexander Hodkinson (A)

National Institute of Health Research School for Primary Care Research, Division of Population Health, Health Services Research & Primary Care, University of Manchester, Manchester, England.

Peter A Coventry (PA)

Department of Health Sciences, University of York, York, England.

Salwa S Zghebi (SS)

National Institute of Health Research School for Primary Care Research, Division of Population Health, Health Services Research & Primary Care, University of Manchester, Manchester, England.

Evangelos Kontopantelis (E)

Faculty of Biology, Medicine and Health, Division of Informatics, Imaging and Data Sciences, University of Manchester, Manchester, England.

Peter Bower (P)

National Institute of Health Research School for Primary Care Research, Division of Population Health, Health Services Research & Primary Care, University of Manchester, Manchester, England.

Karina Lovell (K)

Division of Nursing, Midwifery and Social Work, School of Health Sciences, University of Manchester, Manchester, England; Greater Manchester Mental Health NHS Foundation Trust, Manchester, England.

Simon Gilbody (S)

Department of Health Sciences, Hull York Medical School, HYMS, University of York, York, England.

Waquas Waheed (W)

National Institute of Health Research School for Primary Care Research, Division of Population Health, Health Services Research & Primary Care, University of Manchester, Manchester, England.

Christopher Dickens (C)

Mental Health Research Group, University of Exeter Medical School, England.

Janine Archer (J)

School of Health and Society, School of Health and Society, University of Salford, England.

Amy Blakemore (A)

Division of Nursing, Midwifery and Social Work, School of Health Sciences, University of Manchester, Manchester, England.

David A Adler (DA)

Departments of Psychiatry and Medicine, Tufts Medical Center and Tufts University School of Medicine, England.

Enric Aragones (E)

Institut Universitari d'Investigació en Atenció Primària Jordi Gol (IDIAPJGol), Barcelona, Spain.

Cecilia Björkelund (C)

Primary Health Care School of Public Health and Community Medicine, University of Gothenburg, Gothenburg, Sweden.

Martha L Bruce (ML)

Department of Psychiatry, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.

Marta Buszewicz (M)

Institute of Epidemiology and Health, Faculty of Population and Health Sciences, University College London, London, England.

Robert M Carney (RM)

Department of Psychiatry, Washington University in St. Louis (WUSTL), St. Louis, Missouri, USA.

Martin G Cole (MG)

Department of Psychiatry, St. Mary's Hospital Center, McGill University, Montreal, Quebec, Canada.

Karina W Davidson (KW)

Institute of Health Innovations and Outcomes Research, Feinstein Institutes for Medical Research, Northwell Health, Manhasset, New York, USA.

Jochen Gensichen (J)

Institute of General Practice and Family Medicine, LMU Klinikum, Ludwig-Maximilians, University Munich Pettenkoferstr. 10, 80336 Munich, Germany.

Nancy K Grote (NK)

School of Social Work, University of Washington, Seattle, USA.

Joan Russo (J)

Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, USA.

Klaas Huijbregts (K)

Department of Psychiatry and Amsterdam Public Health Research Institute, Amsterdam, Netherlands.

Jeff C Huffman (JC)

Harvard Medical School, Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts.

Marco Menchetti (M)

Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy.

Vikram Patel (V)

The Pershing Square Professor of Global Health, Harvard Medical School, Boston, MA, USA.

David A Richards (DA)

Institute of Health Research, University of Exeter College of Medicine and Health, Exeter, England; Western University of Norway, Bergen, Norway.

Bruce Rollman (B)

Center for Behavioral Health, Media and Technology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

Annet Smit (A)

HAN University of Applied Sciences, Nijmegen, Netherlands.

Moniek C Zijlstra-Vlasveld (MC)

ZonMw, The Netherlands Organisation for Health Research and Development, The Hague, Netherlands.

Kenneth B Wells (KB)

Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, USA; Jane and Terry Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, USA.

Thomas Zimmermann (T)

Department of General Practice / Primary Care, Centre for Psychosocial Medicine, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.

Jurgen Unutzer (J)

Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, USA.

Maria Panagioti (M)

National Institute of Health Research School for Primary Care Research, Division of Population Health, Health Services Research & Primary Care, University of Manchester, Manchester, England.

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