Multiscale characterization of ovariectomized rat femur.
Bone micro-CT
Estrogen
Matrix mineralization
Nanoindentation
Osteoporosis
Journal
Journal of biomechanics
ISSN: 1873-2380
Titre abrégé: J Biomech
Pays: United States
ID NLM: 0157375
Informations de publication
Date de publication:
09 06 2021
09 06 2021
Historique:
received:
30
06
2020
revised:
12
02
2021
accepted:
12
04
2021
pubmed:
30
4
2021
medline:
8
7
2021
entrez:
29
4
2021
Statut:
ppublish
Résumé
Estrogen deficiency activates bone resorbing cells (osteoclasts) and to a lesser extent bone forming cells (osteoblasts), resulting in a gap between resorption and formation that leads to a net loss of bone. These cell activities alter bone architecture and tissue composition. Thus, the objective of this study is to examine whether multiscale (10
Identifiants
pubmed: 33915473
pii: S0021-9290(21)00242-6
doi: 10.1016/j.jbiomech.2021.110462
pmc: PMC8166321
mid: NIHMS1699681
pii:
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
110462Subventions
Organisme : NIA NIH HHS
ID : R21 AG033714
Pays : United States
Informations de copyright
Copyright © 2021 Elsevier Ltd. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declared that there is no conflict of interest.
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