The Biomechanics of Cartilage-An Overview.

Articular cartilage biomechanics osteoarthritis tissue engineering viscoelasticity

Journal

Life (Basel, Switzerland)
ISSN: 2075-1729
Titre abrégé: Life (Basel)
Pays: Switzerland
ID NLM: 101580444

Informations de publication

Date de publication:
01 Apr 2021
Historique:
received: 22 02 2021
revised: 21 03 2021
accepted: 26 03 2021
entrez: 30 4 2021
pubmed: 1 5 2021
medline: 1 5 2021
Statut: epublish

Résumé

Articular cartilage (AC) sheathes joint surfaces and minimizes friction in diarthrosis. The resident cell population, chondrocytes, are surrounded by an extracellular matrix and a multitude of proteins, which bestow their unique characteristics. AC is characterized by a zonal composition (superficial (tangential) zone, middle (transitional) zone, deep zone, calcified zone) with different mechanical properties. An overview is given about different testing (load tests) methods as well as different modeling approaches. The widely accepted biomechanical test methods, e.g., the indentation analysis, are summarized and discussed. A description of the biphasic theory is also shown. This is required to understand how interstitial water contributes toward the viscoelastic behavior of AC. Furthermore, a short introduction to a more complex model is given.

Identifiants

pubmed: 33915881
pii: life11040302
doi: 10.3390/life11040302
pmc: PMC8065530
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

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Auteurs

Joerg Eschweiler (J)

Department of Orthopaedic Surgery, RWTH Aachen University Clinic, Pauwelsstraße 30, 52074 Aachen, Germany.

Nils Horn (N)

Department of Orthopaedic Surgery, RWTH Aachen University Clinic, Pauwelsstraße 30, 52074 Aachen, Germany.

Bjoern Rath (B)

Department of Orthopaedic Surgery, Klinikum Wels-Grieskirchen, 4600 Wels, Austria.

Marcel Betsch (M)

Department of Orthopaedic Surgery, Mannheim University Hospital, 68167 Mannheim, Germany.

Alice Baroncini (A)

Department of Orthopaedic Surgery, RWTH Aachen University Clinic, Pauwelsstraße 30, 52074 Aachen, Germany.

Markus Tingart (M)

Department of Orthopaedic Surgery, RWTH Aachen University Clinic, Pauwelsstraße 30, 52074 Aachen, Germany.

Filippo Migliorini (F)

Department of Orthopaedic Surgery, RWTH Aachen University Clinic, Pauwelsstraße 30, 52074 Aachen, Germany.

Classifications MeSH