Tertiary Prevention of HCC in Chronic Hepatitis B or C Infected Patients.

carcinogenesis cirrhosis direct acting antiviral agents interferon nucleos(t)ide analogues sustained virologic response

Journal

Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829

Informations de publication

Date de publication:
06 Apr 2021
Historique:
received: 16 03 2021
revised: 29 03 2021
accepted: 29 03 2021
entrez: 30 4 2021
pubmed: 1 5 2021
medline: 1 5 2021
Statut: epublish

Résumé

Hepatocellular carcinoma (HCC) ranks as a leading cause of common cancer and cancer-related death. The major etiology of HCC is due to chronic hepatitis virus including HBV and HCV infections. Scheduled HCC surveillance in high risk populations improves the early detection rate and the feasibility of curative treatment. However, high HCC recurrence rate still accounts for the poor prognosis of HCC patients. In this article, we critically review the pathogenesis of viral hepatitis-related hepatocellular carcinoma and the evidence of tertiary prevention efficacy by current available antiviral treatment, and discuss the knowledge gap in viral hepatitis-related HCC tertiary prevention.

Identifiants

pubmed: 33917345
pii: cancers13071729
doi: 10.3390/cancers13071729
pmc: PMC8038691
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Subventions

Organisme : Chang Gung Memorial Hospital, Linkou
ID : CMRPG3J1342, CMRPG3G1281-2, CMRPG3K0841-2, CMRPG3I0271-2
Organisme : National Science Council
ID : NMRPG3H0473
Organisme : Taipei Veterans General Hospital
ID : Center of Excellence for Cancer Research MOHW110-TDU-B-211-144019

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Auteurs

Wei Teng (W)

Department of Gastroenterology and Hepatology, Chang Gung Memorial Hospital, Linkou Medical Center College of Medicine, Chang Gung University, Taiwan NO 5, Fu-Hsing Street, Kuei Shan, Taoyuan City 33305, Taiwan.
College of Medicine, Chang Gung University, Taoyuan City 33302, Taiwan.

Yen-Chun Liu (YC)

Department of Gastroenterology and Hepatology, Chang Gung Memorial Hospital, Linkou Medical Center College of Medicine, Chang Gung University, Taiwan NO 5, Fu-Hsing Street, Kuei Shan, Taoyuan City 33305, Taiwan.
College of Medicine, Chang Gung University, Taoyuan City 33302, Taiwan.

Wen-Juei Jeng (WJ)

Department of Gastroenterology and Hepatology, Chang Gung Memorial Hospital, Linkou Medical Center College of Medicine, Chang Gung University, Taiwan NO 5, Fu-Hsing Street, Kuei Shan, Taoyuan City 33305, Taiwan.
College of Medicine, Chang Gung University, Taoyuan City 33302, Taiwan.

Chien-Wei Su (CW)

Division of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taiwan. No.201, Sec. 2, Shipai Rd., Peitou District, Taipei 11217, Taiwan.
Hospitalist Ward, Department of Medicine, Taipei Veterans General Hospital, Taipei 11217, Taiwan.
Department of Medicine, School of Medicine, National Yang-Ming University School of Medicine, Taipei 11217, Taiwan.
Biomedical Science and Engineering Center, National Tsing Hua University, Hsinchu 30013, Taiwan.

Classifications MeSH