Alteration of Tissue Marking Dyes Depends on Used Chromogen during Immunohistochemistry.
DAB
Diaminobenzidine-tetrahydrochloride-dihydrate
gross section
immunohistochemistry
margin inking
surgical margins
tissue marking
Journal
Cells
ISSN: 2073-4409
Titre abrégé: Cells
Pays: Switzerland
ID NLM: 101600052
Informations de publication
Date de publication:
08 04 2021
08 04 2021
Historique:
received:
09
03
2021
revised:
01
04
2021
accepted:
06
04
2021
entrez:
30
4
2021
pubmed:
1
5
2021
medline:
21
10
2021
Statut:
epublish
Résumé
Pathological biopsy protocols require tissue marking dye (TMD) for orientation. In some cases (e.g., close margin), additional immunohistochemical analyses can be necessary. Therefore, the correlation between the applied TMD during macroscopy and the examined TMD during microscopy is crucial for the correct orientation, the residual tumour status and the subsequent therapeutic regime. In this context, our group observed colour changes during routine immunohistochemistry. Tissue specimens were marked with various TMD and processed by two different methods. TMD (blue, red, black, yellow and green) obtained from three different providers (A, B and C, and Whiteout/Tipp-Ex
Identifiants
pubmed: 33917667
pii: cells10040835
doi: 10.3390/cells10040835
pmc: PMC8068012
pii:
doi:
Substances chimiques
Coloring Agents
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
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