Vaginal Probiotics for Reproductive Health and Related Dysbiosis: Systematic Review and Meta-Analysis.
IVF
VVC
bacterial vaginosis
reproductive dysbiosis
vaginal probiotics
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
02 Apr 2021
02 Apr 2021
Historique:
received:
27
01
2021
revised:
23
03
2021
accepted:
29
03
2021
entrez:
30
4
2021
pubmed:
1
5
2021
medline:
1
5
2021
Statut:
epublish
Résumé
The use of probiotics in reproductive-related dysbiosis is an area of continuous progress due to the growing interest from clinicians and patients suffering from recurrent reproductive microbiota disorders. An imbalance in the natural colonization sites related to reproductive health-vaginal, cervicovaginal, endometrial, and pregnancy-related altered microbiota-could play a decisive role in reproductive outcomes. Oral and vaginal administrations are in continuous discussion regarding the clinical effects pursued, but the oral route is used and studied more often despite the need for further transference to the colonization site. The aim of the present review was to retrieve the standardized protocols of vaginal probiotics commonly used for investigating their microbiota modulation capacities. Most of the studies selected focused on treating bacterial vaginosis (BV) as the most common dysbiosis; a few studies focused on vulvovaginal candidiasis (VVC) and on pretreatment during in vitro fertilization (IVF). Vaginal probiotic doses administered were similar to oral probiotics protocols, ranging from ≥10
Identifiants
pubmed: 33918150
pii: jcm10071461
doi: 10.3390/jcm10071461
pmc: PMC8037567
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Références
Microb Pathog. 2019 Sep;134:103599
pubmed: 31212037
Reprod Biomed Online. 2005 Jul;11(1):71-5
pubmed: 16102292
J Assist Reprod Genet. 2012 Feb;29(2):105-15
pubmed: 22222853
Environ Pollut. 2016 Nov;218:923-930
pubmed: 27554980
Nat Rev Immunol. 2018 Aug;18(8):514-525
pubmed: 29717233
mSystems. 2019 Apr 16;4(2):
pubmed: 31020040
Enferm Infecc Microbiol Clin. 2019 Nov;37(9):592-601
pubmed: 30594321
Nutrients. 2020 Mar 13;12(3):
pubmed: 32182980
Clin Microbiol Infect. 2009 Jan;15(1):67-74
pubmed: 19046169
Front Public Health. 2020 Jun 16;8:225
pubmed: 32612969
FEMS Immunol Med Microbiol. 2003 Mar 20;35(2):131-4
pubmed: 12628548
Nat Med. 2019 Oct;25(10):1500-1504
pubmed: 31591599
Front Microbiol. 2020 Nov 30;11:578007
pubmed: 33329442
Am J Obstet Gynecol. 2020 Apr;222(4):296-305
pubmed: 32057732
Reprod Biomed Online. 2005 Dec;11(6):674-5
pubmed: 16417727
Nature. 2012 Jun 13;486(7402):207-14
pubmed: 22699609
Sci Rep. 2020 May 14;10(1):7976
pubmed: 32409699
Microbiome. 2014 May 27;2:18
pubmed: 24987521
PLoS One. 2018 Dec 26;13(12):e0209205
pubmed: 30586435
PLoS Med. 2009 Jul 21;6(7):e1000097
pubmed: 19621072
Am J Obstet Gynecol. 2004 Jun;190(6):1509-19
pubmed: 15284723
Int J Environ Res Public Health. 2019 Nov 13;16(22):
pubmed: 31766303
PLoS One. 2014 Aug 15;9(8):e104511
pubmed: 25127240
Therap Adv Gastroenterol. 2010 Sep;3(5):307-19
pubmed: 21180611
High Throughput. 2018 Dec 11;7(4):
pubmed: 30544936
Clin Infect Dis. 2015 May 15;60 Suppl 2:S129-34
pubmed: 25922398
Hum Reprod. 2013 Jul;28(7):1809-15
pubmed: 23543384
Int J Antimicrob Agents. 2000 Dec;16(4):531-6
pubmed: 11118874
Nature. 2012 Jun 13;486(7402):215-21
pubmed: 22699610
Ecotoxicol Environ Saf. 2020 Sep 15;201:110726
pubmed: 32480160
Semin Neonatol. 2002 Aug;7(4):259-74
pubmed: 12401296
Biomed Res Int. 2018 Sep 30;2018:7571954
pubmed: 30364031
Environ Int. 2020 Mar;136:105465
pubmed: 31945693
FEMS Immunol Med Microbiol. 2001 Dec;32(1):37-41
pubmed: 11750220
J Food Drug Anal. 2019 Jul;27(3):615-622
pubmed: 31324278
Sex Transm Dis. 2008 Jan;35(1):78-83
pubmed: 17989585
Reprod Biomed Online. 2017 Jul;35(1):103-112
pubmed: 28479120
J Med Food. 2004 Summer;7(2):223-8
pubmed: 15298771
Nature. 2019 Aug;572(7769):329-334
pubmed: 31367035
Indian J Med Res. 2015 Jul;142(1):79-84
pubmed: 26261170
Nat Microbiol. 2018 Aug;3(8):851-853
pubmed: 30046175
J Clin Endocrinol Metab. 2018 Apr 1;103(4):1502-1511
pubmed: 29370410
Cell. 2014 Jul 31;158(3):690-690.e1
pubmed: 25083877
Drug Des Devel Ther. 2015 Sep 25;9:5345-54
pubmed: 26451088
Pathogens. 2019 Oct 24;8(4):
pubmed: 31653041
Fertil Steril. 2018 Aug;110(3):337-343
pubmed: 30098680
Trials. 2011 Nov 08;12:239
pubmed: 22059409
Am J Obstet Gynecol. 2016 Dec;215(6):684-703
pubmed: 27717732
Reprod Med Biol. 2018 Oct 25;18(1):72-82
pubmed: 30655724
Nat Rev Gastroenterol Hepatol. 2020 Nov;17(11):687-701
pubmed: 32826966
Infect Dis Obstet Gynecol. 2012;2012:503648
pubmed: 22701297
FEMS Microbiol Lett. 2019 Feb 1;366(4):
pubmed: 30715301
Clin Microbiol Rev. 2016 Apr;29(2):223-38
pubmed: 26864580
Proc Natl Acad Sci U S A. 2011 Mar 15;108 Suppl 1:4680-7
pubmed: 20534435
Microb Pathog. 2020 Apr;141:104029
pubmed: 32014462
Ann N Y Acad Sci. 2004 Dec;1034:300-15
pubmed: 15731321
PLoS One. 2018 Jun 18;13(6):e0195081
pubmed: 29912913
J Law Med Ethics. 2019 Dec;47(4):555-567
pubmed: 31957577
AMB Express. 2018 Sep 27;8(1):153
pubmed: 30264211
Eur J Obstet Gynecol Reprod Biol. 2013 Mar;167(1):59-63
pubmed: 23199811
BJOG. 2005 Feb;112(2):234-40
pubmed: 15663590
Gut Microbes. 2017 Nov 2;8(6):521-543
pubmed: 28640662
Proc Natl Acad Sci U S A. 2006 Apr 4;103(14):5478-83
pubmed: 16567644
Sci Rep. 2019 Feb 18;9(1):2204
pubmed: 30778155
Nat Microbiol. 2017 Apr 25;2:17057
pubmed: 28440276
PLoS One. 2012;7(4):e34540
pubmed: 22509319
Clin Infect Dis. 2016 Mar 1;62(5):568-573
pubmed: 26611780
Theriogenology. 2010 Jun;73(9):1167-79
pubmed: 20138353
Maturitas. 2017 Sep;103:45-53
pubmed: 28778332
Microbiome. 2017 Apr 28;5(1):48
pubmed: 28454555
Clin Microbiol Infect. 2007 Jul;13(7):657-64
pubmed: 17633390
Sex Transm Dis. 2011 Nov;38(11):1020-7
pubmed: 21992977
BJOG. 2017 Mar;124(4):606-611
pubmed: 28224747
Clin Investig Arterioscler. 2018 Nov - Dec;30(6):271-279
pubmed: 29804899