Does Cannabis, Cocaine and Alcohol Use Impact Differently on Adult Attention Deficit/Hyperactivity Disorder Clinical Picture?

adult ADHD attention deficit hyperactivity disorder dual disorder substance use disorder

Journal

Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588

Informations de publication

Date de publication:
02 Apr 2021
Historique:
received: 09 02 2021
revised: 20 03 2021
accepted: 22 03 2021
entrez: 30 4 2021
pubmed: 1 5 2021
medline: 1 5 2021
Statut: epublish

Résumé

While the association between adult Attention Deficit/Hyperactivity Disorder (A-ADHD) and Substance Use Disorders (SUDs) has been widely explored, less attention has been dedicated to the various substance use variants. In a previous paper, we identified two variants: type 1 (use of stimulants/alcohol) and type 2 (use of cannabinoids). In this study, we compared demographic, clinical and symptomatologic features between Dual Disorder A-ADHD (DD/A-ADHD) patients according to our substance use typology, and A-ADHD without DD (NDD/A-ADHD) ones. NDD patients were more frequently diagnosed as belonging to inattentive ADHD subtype compared with type 1 DD/A-ADHD patients, but not with respect to type 2 DD/ADHD. NDD/A-ADHD patients showed less severe symptoms of hyperactivity/impulsivity than DD/A-ADHD type 1, but not type 2. Type 1 and type 2 patients shared the feature of displaying higher impulsiveness than NDD/A-ADHD ones. General psychopathology scores were more severe in type 2 DD/ADHD patients, whereas type 1 patients showed greater similarity to NDD/A-ADHD. Legal problems were more strongly represented in type 1 than in type 2 patients or NDD/A-ADHD ones. Our results suggest that type 1 and type 2 substance use differ in their effects on A-ADHD patients-an outcome that brings with it different likely implications in dealing with the diagnostic and therapeutic processes.

Identifiants

pubmed: 33918432
pii: jcm10071481
doi: 10.3390/jcm10071481
pmc: PMC8038274
pii:
doi:

Types de publication

Journal Article

Langues

eng

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Auteurs

Vincenza Spera (V)

Psychiatric Clinic, Sociopsychiatric Organization, 6850 Mendrisio, Switzerland.

Alessandro Pallucchini (A)

PISA-School of Experimental and Clinical Psychiatry, 56100 Pisa, Italy.

Marco Carli (M)

School of Clinical Pharmacology, Department of Clinical and Experimental Medicine, University of Pisa, 56100 Pisa, Italy.

Marco Maiello (M)

PISA-School of Experimental and Clinical Psychiatry, 56100 Pisa, Italy.

Angelo G I Maremmani (AGI)

PISA-School of Experimental and Clinical Psychiatry, 56100 Pisa, Italy.
North-Western Tuscany Local Health Unit, Department of Psychiatry, Tuscany NHS, Versilia Zone, 55045 Viareggio, Italy.
Association for the Application of Neuroscientific Knowledge to Social Aims (AU-CNS), Pietrasanta, 55045 Lucca, Italy.

Giulio Perugi (G)

2nd Psychiatric Unit, Department of Clinical and Experimental Medicine, Santa Chiara University Hospital, University of Pisa, 56100 Pisa, Italy.

Icro Maremmani (I)

Association for the Application of Neuroscientific Knowledge to Social Aims (AU-CNS), Pietrasanta, 55045 Lucca, Italy.
Vincent P. Dole Dual Disorder Unit, 2nd Psychiatric Unit, Santa Chiara University Hospital, University of Pisa, 56100 Pisa, Italy.
G. De Lisio Institute of Behavioral Sciences, 56121 Pisa, Italy.
Saint Camillus International University of Health and Medical Sciences-UniCamillus, 00131 Rome, Italy.

Classifications MeSH