Persistent Ventricle Partitioning in the Adult Zebrafish Heart.

cardiac ventricle first heart field heart development lineage tracing zebrafish

Journal

Journal of cardiovascular development and disease
ISSN: 2308-3425
Titre abrégé: J Cardiovasc Dev Dis
Pays: Switzerland
ID NLM: 101651414

Informations de publication

Date de publication:
09 Apr 2021
Historique:
received: 15 03 2021
revised: 02 04 2021
accepted: 07 04 2021
entrez: 30 4 2021
pubmed: 1 5 2021
medline: 1 5 2021
Statut: epublish

Résumé

The vertebrate heart integrates cells from the early-differentiating first heart field (FHF) and the later-differentiating second heart field (SHF), both emerging from the lateral plate mesoderm. In mammals, this process forms the basis for the development of the left and right ventricle chambers and subsequent chamber septation. The single ventricle-forming zebrafish heart also integrates FHF and SHF lineages during embryogenesis, yet the contributions of these two myocardial lineages to the adult zebrafish heart remain incompletely understood. Here, we characterize the myocardial labeling of FHF descendants in both the developing and adult zebrafish ventricle. Expanding previous findings, late gastrulation-stage labeling using

Identifiants

pubmed: 33918756
pii: jcdd8040041
doi: 10.3390/jcdd8040041
pmc: PMC8070482
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
ID : 310030_179213
Organisme : Novartis Foundation for medical-biological research
ID : 18A032
Organisme : the Department of Pediatrics, University of Colorado School of Medicine Anschutz Medical Campus
ID : USA
Organisme : Children's Hospital Colorado Foundation
ID : USA

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Auteurs

Catherine Pfefferli (C)

Department of Biology, University of Fribourg, Chemin du Musée 10, 1700 Fribourg, Switzerland.

Hannah R Moran (HR)

Department of Pediatrics, Section of Developmental Biology, University of Colorado School of Medicine and Children's Hospital Colorado, Anschutz Medical Campus, Aurora, CO 80045, USA.

Anastasia Felker (A)

Department of Pediatrics, Section of Developmental Biology, University of Colorado School of Medicine and Children's Hospital Colorado, Anschutz Medical Campus, Aurora, CO 80045, USA.

Christian Mosimann (C)

Department of Pediatrics, Section of Developmental Biology, University of Colorado School of Medicine and Children's Hospital Colorado, Anschutz Medical Campus, Aurora, CO 80045, USA.

Anna Jaźwińska (A)

Department of Biology, University of Fribourg, Chemin du Musée 10, 1700 Fribourg, Switzerland.

Classifications MeSH