Preparation, Characterization, Swelling Potential, and In-Vitro Evaluation of Sodium Poly(Styrene Sulfonate)-Based Hydrogels for Controlled Delivery of Ketorolac Tromethamine.

dynamic swelling and in-vitro percent drug release hydrogels sol-gel analysis

Journal

Pharmaceuticals (Basel, Switzerland)
ISSN: 1424-8247
Titre abrégé: Pharmaceuticals (Basel)
Pays: Switzerland
ID NLM: 101238453

Informations de publication

Date de publication:
09 Apr 2021
Historique:
received: 04 03 2021
revised: 31 03 2021
accepted: 07 04 2021
entrez: 30 4 2021
pubmed: 1 5 2021
medline: 1 5 2021
Statut: epublish

Résumé

The objective of the current study work was to fabricate sodium poly(styrene sulfonate-co-poly acrylic acid) (SPSPAA) hydrogels by using a free radical co-polymerization method for controlled delivery of ketorolac tromethamine (KT). Polymer (sodium poly(styrene sulfonate) (SPS) polymerized with monomer acrylic acid (AA) in the presence of initiator ammonium peroxodisulfate (APS) and cross-linker

Identifiants

pubmed: 33918921
pii: ph14040350
doi: 10.3390/ph14040350
pmc: PMC8069699
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : National Science Council
ID : MOST 109-2320-B-037-0025
Organisme : Zuoying Branch of Kaohsiung Armed Forces General Hospital
ID : KAFGH-ZY-A-11026

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Auteurs

Muhammad Suhail (M)

School of Pharmacy, Kaohsiung Medical University, 100 Shih-Chuan 1st Road, Kaohsiung City 80708, Taiwan.

Chih-Wun Fang (CW)

Divison of Pharmacy, Zuoying Branch of Kaohsiung Armed Forces General Hospital. No. 553, Junxiao Rd., Zuoying Dist., Kaohsiung City 81342, Taiwan.

Muhammad Usman Minhas (MU)

College of Pharmacy, University of Sargodha, Sargodha 40100, Pakistan.

Pao-Chu Wu (PC)

School of Pharmacy, Kaohsiung Medical University, 100 Shih-Chuan 1st Road, Kaohsiung City 80708, Taiwan.
Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung 80708, Taiwan.
Drug Development and Value Creation Research Center, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.

Classifications MeSH