New In Vitro Coculture Model for Evaluating Intestinal Absorption of Different Lipid Nanocapsules.
Caco-2
HMEC-1
apparent permeability
förster resonance energy transfer
intestinal absorption
lipid nanocapsule
Journal
Pharmaceutics
ISSN: 1999-4923
Titre abrégé: Pharmaceutics
Pays: Switzerland
ID NLM: 101534003
Informations de publication
Date de publication:
21 Apr 2021
21 Apr 2021
Historique:
received:
06
04
2021
revised:
19
04
2021
accepted:
20
04
2021
entrez:
30
4
2021
pubmed:
1
5
2021
medline:
1
5
2021
Statut:
epublish
Résumé
Standard models used for evaluating the absorption of nanoparticles like Caco-2 ignore the presence of vascular endothelium, which is a part of the intestinal multi-layered barrier structure. Therefore, a coculture between the Caco-2 epithelium and HMEC-1 (Human Microvascular Endothelial Cell type 1) on a Transwell
Identifiants
pubmed: 33919334
pii: pharmaceutics13050595
doi: 10.3390/pharmaceutics13050595
pmc: PMC8143299
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Ligue contre le cancer
ID : JPB/FP - 223/12.2020
Organisme : Région Pays de la Loire - Pulsar
ID : IntendNano
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