Endothelin ET
Alzheimer’s disease
ETB receptor
brain ischemia
endothelin
neuropathic pain
reactive astrocyte
traumatic brain injury
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
21 Apr 2021
21 Apr 2021
Historique:
received:
15
03
2021
revised:
16
04
2021
accepted:
19
04
2021
entrez:
30
4
2021
pubmed:
1
5
2021
medline:
20
5
2021
Statut:
epublish
Résumé
In brain disorders, reactive astrocytes, which are characterized by hypertrophy of the cell body and proliferative properties, are commonly observed. As reactive astrocytes are involved in the pathogenesis of several brain disorders, the control of astrocytic function has been proposed as a therapeutic strategy, and target molecules to effectively control astrocytic functions have been investigated. The production of brain endothelin-1 (ET-1), which increases in brain disorders, is involved in the pathophysiological response of the nervous system. Endothelin B (ET
Identifiants
pubmed: 33919338
pii: ijms22094333
doi: 10.3390/ijms22094333
pmc: PMC8122402
pii:
doi:
Substances chimiques
Endothelin-1
0
Receptor, Endothelin B
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Japan Society for the Promotion of Science
ID : 18K06695
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