A Phase II Study on the Use of Convalescent Plasma for the Treatment of Severe COVID-19- A Propensity Score-Matched Control Analysis.
COVID-19
SARS-CoV-2 antibodies
convalescent plasma
efficacy
Journal
Microorganisms
ISSN: 2076-2607
Titre abrégé: Microorganisms
Pays: Switzerland
ID NLM: 101625893
Informations de publication
Date de publication:
11 Apr 2021
11 Apr 2021
Historique:
received:
20
03
2021
revised:
01
04
2021
accepted:
09
04
2021
entrez:
30
4
2021
pubmed:
1
5
2021
medline:
1
5
2021
Statut:
epublish
Résumé
COVID-19 is a global pandemic associated with increased morbidity and mortality. Convalescent plasma (CP) infusion is a strategy of potential therapeutic benefit. We conducted a multicenter phase II study to evaluate the efficacy and safety of CP in patients with COVID-19, grade 4 or higher. To evaluate the efficacy of CP, a matched propensity score analysis was used comparing the intervention (
Identifiants
pubmed: 33920489
pii: microorganisms9040806
doi: 10.3390/microorganisms9040806
pmc: PMC8069820
pii:
doi:
Banques de données
ClinicalTrials.gov
['NCT04408209']
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : NCI NIH HHS
ID : No grant.
Pays : United States
Organisme : SYNENOSIS
ID : No grant.
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