Synthesis and Bioactivities of Marine Pyran-Isoindolone Derivatives as Potential Antithrombotic Agents.

Apoptosis / drug effects Cell Survival / drug effects Fibrinolysis / drug effects Fibrinolytic Agents / chemical synthesis HeLa Cells Humans Isoindoles / chemical synthesis Molecular Structure Pyrans / chemical synthesis Stachybotrys / metabolism Structure-Activity Relationship
Pro-uPA-catalyzed plasminogen antithrombotic agents fibrinolytic activity modification pyran-isoindolone derivatives

Journal

Marine drugs
ISSN: 1660-3397
Titre abrégé: Mar Drugs
Pays: Switzerland
ID NLM: 101213729

Informations de publication

Date de publication:
15 Apr 2021
Historique:
received: 15 03 2021
revised: 09 04 2021
accepted: 13 04 2021
entrez: 30 4 2021
pubmed: 1 5 2021
medline: 8 6 2021
Statut: epublish

Résumé

2,5-Bis-[8-(4,8-dimethyl-nona-3,7-dienyl)-5,7-dihydroxy-8-methyl-3-keto-1,2,7,8-teraahydro-6

Identifiants

DOI: 10.3390/md19040218 PMID: 33921137 PMC: PMC8071544
pubmed: 33921137
pii: md19040218
doi: 10.3390/md19040218
pmc: PMC8071544
pii:
doi:

Substances chimiques

Fibrinolytic Agents 0
Isoindol-1-one 0
Isoindoles 0
Pyrans 0

Types de publication

Comparative Study Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : NSFC-Liaoning Joint Fund
ID : No. 81502955
Organisme : the Doctoral Scientific Research Foundation of Shanghai Ocean University
ID : No. A2030214300077
Organisme : the Young Teachers Training Program of Shanghai
ID : No. A12056160002
Organisme : the Plan of Innovation Action in Shanghai
ID : No. 14431906000
Organisme : Ruilong Sheng
ID : M1420-01-0145-FEDER-000005-Centro de Química da Madeira-CQM+(Madeira 14-20)
Organisme : Ruilong Sheng
ID : ARDITI-2017-ISG-00
Organisme : Portuguese Government funds
ID : project PEst-OE/QUI/UI0674/2019, CQM

Références

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Auteurs

Yinan Wang (Y)

College of Food Science and Technology, Shanghai Ocean University, Shanghai 201306, China.

Hui Chen (H)

Shanghai Engineering Research Center of Hadal Science and Technology, College of Marine Sciences, Shanghai Ocean University, Shanghai 201306, China.

Ruilong Sheng (R)

CQM-Centro de Química da Madeira, Campus da Penteada, Universidade da Madeira, 9000-390 Funchal, Portugal.
ORCID: 0000-0002-3303-3832

Zhe Fu (Z)

College of Food Science and Technology, Shanghai Ocean University, Shanghai 201306, China.

Junting Fan (J)

School of Pharmacy, Nanjing Medical University, Nanjing 211166, China.

Wenhui Wu (W)

College of Food Science and Technology, Shanghai Ocean University, Shanghai 201306, China.
ORCID: 0000-0002-1710-8582

Qidong Tu (Q)

School of Pharmacy, Jiangxi Science and Technology Normal University, Nanchang 330013, China.

Ruihua Guo (R)

College of Food Science and Technology, Shanghai Ocean University, Shanghai 201306, China.
Shanghai Engineering Research Center of Aquatic-Product Processing & Preservation, Shanghai 201306, China.
Laboratory of Quality and Safety Risk Assessment for Aquatic Products on Storage and Preservation (Shanghai), Ministry of Agriculture, Shanghai 201306, China.
ORCID: 0000-0001-8414-886X

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Classifications MeSH

questionsmedicales.fr › Phénomènes physiologiques cellulaires › Mort cellulaire › Mort cellulaire régulée › Apoptose › Synthesis and Bioactivities of Marine...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Survie cellulaire › Synthesis and Bioactivities of Marine...
questionsmedicales.fr › Phénomènes physiologiques respiratoires et circulatoires › Phénomènes physiogiques du sang › Hémostase › Coagulation sanguine › Fibrinolyse › Synthesis and Bioactivities of Marine...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Agents hématologiques › Fibrinolytiques › Synthesis and Bioactivities of Marine...
questionsmedicales.fr › Cellules › Cellules épithéliales › Cellules HeLa › Synthesis and Bioactivities of Marine...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Synthesis and Bioactivities of Marine...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Isoindoles › Synthesis and Bioactivities of Marine...
questionsmedicales.fr › Phénomènes chimiques › Structure moléculaire › Synthesis and Bioactivities of Marine...
questionsmedicales.fr › Composés hétérocycliques › Composés hétéromonocycliques › Pyrannes › Synthesis and Bioactivities of Marine...
questionsmedicales.fr › Eucaryotes › Champignons › Deuteromycota › Stachybotrys › Synthesis and Bioactivities of Marine...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes pharmacologiques › Relation structure-activité › Synthesis and Bioactivities of Marine...