Meningioma Surgery in Patients ≥70 Years of Age: Clinical Outcome and Validation of the SKALE Score.
KPS
SKALE score
elderly
meningioma
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
22 Apr 2021
22 Apr 2021
Historique:
received:
21
03
2021
revised:
18
04
2021
accepted:
20
04
2021
entrez:
30
4
2021
pubmed:
1
5
2021
medline:
1
5
2021
Statut:
epublish
Résumé
Along with increasing average life expectancy, the number of elderly meningioma patients has grown proportionally. Our aim was to evaluate whether these specific patients benefit from surgery and to investigate a previously published score for decision-making in meningioma patients (SKALE). Of 421 patients who underwent primary intracranial meningioma resection between 2009 and 2015, 71 patients were ≥70 years of age. We compared clinical data including World Health Organization (WHO) grade, MIB-1 proliferation index, Karnofsky Performance Status Scale (KPS), progression free survival (PFS) and mortality rate between elderly and all other meningioma patients. Preoperative SKALE scores (Sex, KPS, ASA score, location and edema) were determined for elderly patients. SKALE ≥8 was set for dichotomization to determine any association with outcome parameters. In 71 elderly patients (male/female 37/34) all data were available. Postoperative KPS was significantly lower in elderly patients (
Identifiants
pubmed: 33922009
pii: jcm10091820
doi: 10.3390/jcm10091820
pmc: PMC8122404
pii:
doi:
Types de publication
Journal Article
Langues
eng
Références
Acta Neurochir (Wien). 2013 Dec;155(12):2263-71; discussion 2271
pubmed: 24026231
World Neurosurg. 2018 Jun;114:e1057-e1065
pubmed: 29605697
J Neurol Neurosurg Psychiatry. 2010 May;81(5):502-5
pubmed: 19828483
Zentralbl Neurochir. 2008 Nov;69(4):182-6
pubmed: 18949683
Acta Neurochir (Wien). 2011 Jul;153(7):1501-8; discussion 1508
pubmed: 21562736
Acta Neurochir (Wien). 1990;107(1-2):47-55
pubmed: 2096608
Neuro Oncol. 2015 Jan;17(1):116-21
pubmed: 25100872
Neurochirurgie. 2018 Mar;64(1):5-14
pubmed: 25249493
Surg Neurol. 1987 Apr;27(4):319-22
pubmed: 3824137
Acta Neurochir (Wien). 2015 Sep;157(9):1549-57; discussion 1557
pubmed: 26170189
J Neuropathol Exp Neurol. 1957 Jul;16(3):337-40
pubmed: 13439397
Cancer. 2015 Jul 15;121(14):2400-10
pubmed: 25872752
Neurosurgery. 2007 Nov;61(5):950-4; discussion 955
pubmed: 18091271
J Neurooncol. 2013 Sep;114(2):219-27
pubmed: 23737294
Neurosurg Rev. 2014 Jul;37(3):425-9; discussion 429
pubmed: 24777642
J Clin Neurosci. 2018 Oct;56:63-66
pubmed: 30031568
Neurosurgery. 2012 Mar;70(3):555-65
pubmed: 21866064
J Neurooncol. 2016 Sep;129(2):281-8
pubmed: 27311730
Acta Neurol Scand. 2013 Mar;127(3):161-9
pubmed: 22725678
Neuro Oncol. 2018 Oct 1;20(suppl_4):iv1-iv86
pubmed: 30445539
J Neurosurg. 2017 Apr;126(4):1201-1211
pubmed: 27257838
J Neurosurg. 2005 Feb;102(2):290-4
pubmed: 15739557
Biomed Res Int. 2015;2015:868401
pubmed: 26101778
World Neurosurg. 2011 Feb;75(2):279-85
pubmed: 21492731
BMC Cancer. 2019 Jan 23;19(1):100
pubmed: 30674295
Neurosurgery. 1995 Feb;36(2):270-4
pubmed: 7731506
J Neurooncol. 2010 Sep;99(3):307-14
pubmed: 20821343