A Pilot Clinical Study on Post-Operative Recurrence Provides Biological Clues for a Role of
Candida
Crohn’s
immune sensing
Journal
Journal of fungi (Basel, Switzerland)
ISSN: 2309-608X
Titre abrégé: J Fungi (Basel)
Pays: Switzerland
ID NLM: 101671827
Informations de publication
Date de publication:
22 Apr 2021
22 Apr 2021
Historique:
received:
24
03
2021
revised:
15
04
2021
accepted:
16
04
2021
entrez:
30
4
2021
pubmed:
1
5
2021
medline:
1
5
2021
Statut:
epublish
Résumé
This study prompted by growing evidence of the relationship between the yeast Mycological samples (mouth swabs and stools) and serum samples were collected from 28 CD patients randomized to receive either FCZ ( 1, 2, 3, and 6 months after surgery, endoscopy revealed recurrence in 5/12 (41.7%) patients in the FCZ group and 5/9 (55.6%) in the placebo group, the small cohort preventing any clinical conclusions. In both groups, surgery was followed by a marked decrease in Several combinations of biomarkers of adaptive and innate immunity targeting
Sections du résumé
BACKGROUND AND AIMS
OBJECTIVE
This study prompted by growing evidence of the relationship between the yeast
METHODS
METHODS
Mycological samples (mouth swabs and stools) and serum samples were collected from 28 CD patients randomized to receive either FCZ (
RESULTS
RESULTS
1, 2, 3, and 6 months after surgery, endoscopy revealed recurrence in 5/12 (41.7%) patients in the FCZ group and 5/9 (55.6%) in the placebo group, the small cohort preventing any clinical conclusions. In both groups, surgery was followed by a marked decrease in
CONCLUSION
CONCLUSIONS
Several combinations of biomarkers of adaptive and innate immunity targeting
Identifiants
pubmed: 33922391
pii: jof7050324
doi: 10.3390/jof7050324
pmc: PMC8146386
pii:
doi:
Banques de données
ClinicalTrials.gov
['NCT02997059']
Types de publication
Journal Article
Langues
eng
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