Anti-Inflammatory and Anti-Oxidative Synergistic Effect of Vitamin D and Nutritional Complex on Retinal Pigment Epithelial and Endothelial Cell Lines against Age-Related Macular Degeneration.
8-Hydroxy-2'-Deoxyguanosine
/ metabolism
Anti-Inflammatory Agents
/ pharmacology
Antioxidants
/ pharmacology
Apoptosis
/ drug effects
Cell Line
Cell Proliferation
/ drug effects
Cytokines
/ metabolism
Endothelial Cells
/ drug effects
Humans
Macular Degeneration
/ pathology
Oxidation-Reduction
/ drug effects
Oxidative Stress
/ drug effects
Retinal Pigment Epithelium
/ drug effects
Vitamin D
/ pharmacology
AMD
inflammation
nutritional complex
oxidative stress
retina
vitamin D
Journal
Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595
Informations de publication
Date de publication:
23 Apr 2021
23 Apr 2021
Historique:
received:
18
02
2021
revised:
08
04
2021
accepted:
21
04
2021
entrez:
30
4
2021
pubmed:
1
5
2021
medline:
27
5
2021
Statut:
epublish
Résumé
Age-related macular degeneration (AMD) is a multifactorial disease of the retina featured by dysfunction of retinal pigmented epithelial (RPE) and loss of photoreceptor cells under oxidative stress and inflammatory conditions. Vitamin D and antioxidants have beneficial effects against retinal degenerative diseases, such as AMD. We investigated the impact of associating vitamin D (ND) with a nutritional antioxidant complex (Nutrof Total
Identifiants
pubmed: 33922669
pii: nu13051423
doi: 10.3390/nu13051423
pmc: PMC8170899
pii:
doi:
Substances chimiques
Anti-Inflammatory Agents
0
Antioxidants
0
Cytokines
0
Vitamin D
1406-16-2
8-Hydroxy-2'-Deoxyguanosine
88847-89-6
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
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