Increased Creatine Kinase May Predict A Worse COVID-19 Outcome.

CK CPK SARS-CoV-2 coronavirus myopathy

Journal

Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588

Informations de publication

Date de publication:
16 Apr 2021
Historique:
received: 06 03 2021
revised: 06 04 2021
accepted: 15 04 2021
entrez: 30 4 2021
pubmed: 1 5 2021
medline: 1 5 2021
Statut: epublish

Résumé

Early reports from Asia suggested that increased serum levels of the muscular enzyme creatine-(phospho)-kinase (CK/CPK) could be associated with a more severe prognosis in COVID-19. The aim of this single-center retrospective cohort study of 331 consecutive COVID-19 patients who were hospitalized during Italy's "first wave" was to verify this relationship, and to evaluate the role of possible confounding factors (age, body mass index, gender, and comorbidities). We subdivided our cohort in two groups, based on "severe" (

Identifiants

pubmed: 33923719
pii: jcm10081734
doi: 10.3390/jcm10081734
pmc: PMC8073399
pii:
doi:

Types de publication

Journal Article

Langues

eng

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Auteurs

Daniele Orsucci (D)

Unit of Neurology, San Jacopo Hospital, 51100 Pistoia, Italy.
Unit of Neurology, San Luca Hospital, 55100 Lucca, Italy.

Michele Trezzi (M)

Unit of Infectious Diseases, San Jacopo Hospital, 51100 Pistoia, Italy.

Roberto Anichini (R)

Unit of Diabetology, San Jacopo Hospital, 51100 Pistoia, Italy.

Pierluigi Blanc (P)

Unit of Infectious Diseases, San Jacopo Hospital, 51100 Pistoia, Italy.

Leandro Barontini (L)

Intensive Care Unit, San Jacopo Hospital, 51100 Pistoia, Italy.

Carlo Biagini (C)

Unit of Geriatry, San Jacopo Hospital, 51100 Pistoia, Italy.

Alessandro Capitanini (A)

Unit of Nephrology, San Jacopo Hospital, 51100 Pistoia, Italy.

Marco Comeglio (M)

Unit of Cardiology, San Jacopo Hospital, 51100 Pistoia, Italy.

Paulo Corsini (P)

Department of Laboratory Medicine, San Jacopo Hospital, 51100 Pistoia, Italy.

Federico Gemignani (F)

Department of Internal Medicine, San Jacopo Hospital, 51100 Pistoia, Italy.

Roberto Giannecchini (R)

Department of Laboratory Medicine, San Jacopo Hospital, 51100 Pistoia, Italy.

Massimo Giusti (M)

Department of Internal Medicine, San Jacopo Hospital, 51100 Pistoia, Italy.

Mario Lombardi (M)

Unit of Gastroenterology, San Jacopo Hospital, 51100 Pistoia, Italy.

Elena Marrucci (E)

Department of Internal Medicine, San Jacopo Hospital, 51100 Pistoia, Italy.

Alessandro Natali (A)

Unit of Gastroenterology, San Jacopo Hospital, 51100 Pistoia, Italy.

Gabriele Nenci (G)

Department of Internal Medicine, San Jacopo Hospital, 51100 Pistoia, Italy.

Franco Vannucci (F)

Unit of Pulmonology, San Jacopo Hospital, 51100 Pistoia, Italy.

Gino Volpi (G)

Unit of Neurology, San Jacopo Hospital, 51100 Pistoia, Italy.

Classifications MeSH